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Our study uses CRIPSR targeting vectors to the ALK and ELM4 genes a. What is the...
Our study uses CRIPSR targeting vectors to the ALK and ELM4 genes. What is the ALK...
Our study uses CRIPSR targeting vectors to the ALK and ELM4 genes. What is the ALK gene and normal function (include signaling pathway)? - Anaplastic lymphoma kinase is an enzyme that is encoded by the ALK gene in humans. It plays a significant role in cellular communication, normal development and function of the nervous system, and plays crucial roles in adult behavior. What type of cancer is associated with mutation of the ALK and EML4 genes? - It is associated...
Please help with answers to these questions answer the ones that are straightforward like this one...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
please answer all the question to get a like. Part III Dr. Hernandez sits down with...
please answer all the question to get a like. Part III Dr. Hernandez sits down with Ann and her partner. The doctor is sorry to report that Ann has breast cancer; however, because it was caught early and responds to estrogen and progesterone, the prognosis is good. At this point it looks like the cancer is stage 1. However, as Ann is young, the doctor wants to perform a couple of tests. The first test is a genetic sequencing test...
32. Study the signaling pathway illustrated below, which involves two different receptors. Assume that a protein...
32. Study the signaling pathway illustrated below, which involves two different receptors. Assume that a protein is active only when it is activated, but not inhibited, by its upstream signaling molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively. Assume that the transcription regulator can be activated by either the binding protein or the kinase that are immediately upstream of the transcription factor. Under which of the following conditions will the expression of target:gene "X" be induced?...
(1) Explain the specific role of homeotic genes in controlling animal development; what specific aspect of...
(1) Explain the specific role of homeotic genes in controlling animal development; what specific aspect of development is controlled by homeotic genes, and how do they achieve this? (5 pts) (ii) Explain why a mutation to a homeotic gene can be an important macroevolutionary event. Your response should include a clear discussion of what macroevolution means and the type of evolutionary change associated with macroevolution (as opposed to microevolution), and why mutations to homeotic genes can result in macroevolution. (6...
t cells that are wildtype for the genes in the adenine pathway are of growing on...
t cells that are wildtype for the genes in the adenine pathway are of growing on minimal media lacking adenine. In parallel experiments, we O treat a wildtype culture of yeast cells with one of three mutagens: nitrous acid (a deaminating agent), UV light, and the intercalating agent, acridine orange. We obtain several adenine deficient colonies [ade- with each of the treatments and one mutant from each treatment condition is chosen for further analysis. DNA sequence analysis reveals that each...
In a recent study, the expression profiles for 6900 genes in normal and malignant breast tissues...
In a recent study, the expression profiles for 6900 genes in normal and malignant breast tissues from rats were compared. RNA was extracted using the following tissues: a. breast tissue from virgin rats b. breast tissue from pregnant rats c. breast tissue from lactating rats d. breast carcinomas induced by the meat-derived carcinogen, PhIP e. breast carcinomas induced by the experimental carcinogen, DMBA Tissues a, b, c were grouped together as normal and tissues d, e were grouped as carcinoma...
explain 1 or 2 molecular details in how epigenetics may allow melanoma cells to outsmart BRAF inhibitors **This is for a genetics course Seope: This science commentary claims that epigeneties pl...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
1.) You are studying a particular type of cancer. You observe that the cells are expressing...
1.) You are studying a particular type of cancer. You observe that the cells are expressing higher than normal levels of the activated version of the G protein Ras (ie, they contain more Ras-GTP than normal). a.(2 pts) Further study shows that the one of the Ras genes has been mutated, would you classify this as the mutation of a tumor-suppressor gene or an oncogene? b.(2 pts) Given your knowledge of the regulation of G proteins, suggest an explanation for...
The Case Study in Cancer Part I Ann is a 27-year-old nurse working at the local...
The Case Study in Cancer Part I Ann is a 27-year-old nurse working at the local hospital in surgery. She had worked hard to move into the specialty, and she was enjoying her career, friends, and family. She and her partner had been living together for about a year, and she was content. As a nurse, Ann knew the importance of doing breast self-exams, and did them regularly. In the shower one morning, she felt a lump she wasn’t familiar...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
32. Study the signaling pathway illustrated below, which involves two different receptors. Assume that a protein is active only when it is activated, but not inhibited, by its upstream signaling molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively. Assume that the transcription regulator can be activated by either the binding protein or the kinase that are immediately upstream of the transcription factor. Under which of the following conditions will the expression of target:gene "X" be induced?...
(1) Explain the specific role of homeotic genes in controlling animal development; what specific aspect of development is controlled by homeotic genes, and how do they achieve this? (5 pts) (ii) Explain why a mutation to a homeotic gene can be an important macroevolutionary event. Your response should include a clear discussion of what macroevolution means and the type of evolutionary change associated with macroevolution (as opposed to microevolution), and why mutations to homeotic genes can result in macroevolution. (6...
t cells that are wildtype for the genes in the adenine pathway are of growing on minimal media lacking adenine. In parallel experiments, we O treat a wildtype culture of yeast cells with one of three mutagens: nitrous acid (a deaminating agent), UV light, and the intercalating agent, acridine orange. We obtain several adenine deficient colonies [ade- with each of the treatments and one mutant from each treatment condition is chosen for further analysis. DNA sequence analysis reveals that each...
In a recent study, the expression profiles for 6900 genes in normal and malignant breast tissues from rats were compared. RNA was extracted using the following tissues: a. breast tissue from virgin rats b. breast tissue from pregnant rats c. breast tissue from lactating rats d. breast carcinomas induced by the meat-derived carcinogen, PhIP e. breast carcinomas induced by the experimental carcinogen, DMBA Tissues a, b, c were grouped together as normal and tissues d, e were grouped as carcinoma...
explain 1 or 2 molecular details in how epigenetics may allow
melanoma cells to outsmart BRAF inhibitors
**This is for a genetics course
Seope: This science commentary claims that epigeneties plays a role in cancer cells becoming therapy-resistant. The language used is generalized for the non-scientist and does not include any molecular details, such as methylation of a specific nucleotide in an allele or modification of a specific histone tail amino acid. Your task (individually or in a group of...
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