Homework Answers
Deletion of point mutation of any portion of a chromosome is usually lethal to a diploid organism beacuse it cause genetic imbalance.
Gene amplification may lead to hyperactivity of a particular genes and may lead to conversion of a protooncogene to a oncogene .
Chromosome rearrengment may lead to lethal gene mutations .
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b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS OUTCOME 5. a), Why are Proto-Oncogenes important for...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS
OUTCOME
5. a), Why are Proto-Oncogenes important for the cell cycle control and what is their implication in a progression of tumors and cancers? Provide examples of TWO proto-oncogenes and a type of a cancer each is associated with. (6 pts) b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence relative to gene expression and protein synthesis outcome, assuming each could lead to a development...
Which type of mutation would not typically convert a proto-oncogene, such as beta- catenin, into an...
Which type of mutation would not typically convert a proto-oncogene, such as beta- catenin, into an oncogene? O gene amplification O chromosomal deletion of the region containing the gene O mutation in the coding sequence that leads to the production of a hyperstable or hyperactive protein O chromosomal rearrangement that leads to overproduction of the normal protein DO 10 11 12 9 10 12 se $1 14 15 16 17 18 -13 14 15 16 17 18 13 19 20...
1. Which repair mechanism is most likely affected if the enzyme DNA glycosylase is not functioning...
1. Which repair mechanism is most likely affected if the enzyme DNA glycosylase is not functioning properly? photoreactivation repair base excision repair SOS repair double-strand break repair nucleotide excision repair 2. In bacteria and eukaryotes, a mutation is when ________. In bacteria and eukaryotes, a mutation is when ________. A.the nucleotide sequence in an mRNA molecule is directly changed B.the nucleotide sequence in a DNA molecule is directly changed C.the amino acid sequence in a protein molecule is directly changed...
Review Questions BIOL 260: Chapters 8-10, 13, 19 1. Consider a mutation involving the deletion of...
Review Questions BIOL 260: Chapters 8-10, 13, 19 1. Consider a mutation involving the deletion of either 1, 2, or 3 nucleotides in the DNA of a bacterium. Which of these mutations (ie., deletion of 1, 2, or 3 nucleotides) would likely have the LEAST impact on the organism? Why? Include in your answer a comparison with the other two options to justify your reasoning. Think carefully about the impact each mutation would have on the ultimate protein coded for...
please answer all 6 questions Question 27 3 pts TRBP is a protein important for the...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
13. Why are ribonucleoside triphosphates the monomers required for RNA synthesis rather than ribonucleoside monophosphates? A....
13. Why are ribonucleoside triphosphates the monomers required for RNA synthesis rather than ribonucleoside monophosphates? A. Only ribonucleoside triphosphates contain the sugar ribose. B. Ribonucleoside triphosphates have low potential energy, making the polymerization reaction endergonic. C. Ribonucleoside triphosphates have high potential energy, making the polymerization reaction exergonic. D. Ribonucleoside monophosphates cannot form complementary base pairs with the DNA template. E. Ribonucleoside triphosphates are not used, rather all use deoxyriboside triphosphates. 14. How is a mutation in a bacterial cell that...
please help!! transcription? How could the presence of a hormone in the blood have an effect...
please help!!
transcription? How could the presence of a hormone in the blood have an effect on this structure? 6 points 3. What is an enhancer region and why is it important in the regulation of eukaryotic Contents Cancer Genes that cause cancer are called oncogenes. d. promoter genes. a. operator genes. b. pseudogenes.c 2A mutation in which of the following genes would be LEAST likely lead to a cancer? a. growth hormone gene b. growth hormone receptor gene c....
For Questions 4-18, consider the mutations described in the left-hand column below. Identify whether the Lac operon will be ON or OFF in each of the environments listed across the top. The expression...
For Questions 4-18, consider the mutations described in the left-hand column below. Identify whether the Lac operon will be ON or OFF in each of the environments listed across the top. The expression of the normal (wild type) operon is given. Note that "ON" and "OFF" refer to whether the operon is expressed at high levels (ON) or basal//low/no levels (OFF). (Hint: mutations render the indicated site inactive while leaving the remaining part of the operon or protein functional.) Note...
Short-Answer Questions for Thought and Review 1. Describe three ways in which plasmids can increase the...
Short-Answer Questions for Thought and Review 1. Describe three ways in which plasmids can increase the pathogenic nature of bacteria. 2. Explain what this statement means not always expressed as a phenotype." the information of a genotype is 3. Summarize the differences between prokaryotic and eukarytoic mRNA. 4. Explain why anticodon wobbling is useful to the cell in terms of protection against mistakes and the conservation of anabolic energy that would otherwise have to be spent manufacturing RNAs. 5. Table...
PLEASE COMPUTER TYPED* OR VERY CLEAR HANDWRITING with details 1. Radioactive (14C) uridine (lots of it)...
PLEASE COMPUTER TYPED* OR VERY CLEAR HANDWRITING with
details
1. Radioactive (14C) uridine (lots of it) is added to a growing culture of bacteria for 10 seconds and then the drug rifamycin is added (rifamycin blocks the initiation of transcription, but not continued elongation of RNA polymerases that have already begun transcribing). At two-minute intervals, 1 ml samples are removed and placed on ice. The bacteria are lysed (broken open) and an enzyme is added that will chew up all...
IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS
OUTCOME
5. a), Why are Proto-Oncogenes important for the cell cycle control and what is their implication in a progression of tumors and cancers? Provide examples of TWO proto-oncogenes and a type of a cancer each is associated with. (6 pts) b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence relative to gene expression and protein synthesis outcome, assuming each could lead to a development...
Which type of mutation would not typically convert a proto-oncogene, such as beta- catenin, into an oncogene? O gene amplification O chromosomal deletion of the region containing the gene O mutation in the coding sequence that leads to the production of a hyperstable or hyperactive protein O chromosomal rearrangement that leads to overproduction of the normal protein DO 10 11 12 9 10 12 se $1 14 15 16 17 18 -13 14 15 16 17 18 13 19 20...
Review Questions BIOL 260: Chapters 8-10, 13, 19 1. Consider a mutation involving the deletion of either 1, 2, or 3 nucleotides in the DNA of a bacterium. Which of these mutations (ie., deletion of 1, 2, or 3 nucleotides) would likely have the LEAST impact on the organism? Why? Include in your answer a comparison with the other two options to justify your reasoning. Think carefully about the impact each mutation would have on the ultimate protein coded for...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
13. Why are ribonucleoside triphosphates the monomers required for RNA synthesis rather than ribonucleoside monophosphates? A. Only ribonucleoside triphosphates contain the sugar ribose. B. Ribonucleoside triphosphates have low potential energy, making the polymerization reaction endergonic. C. Ribonucleoside triphosphates have high potential energy, making the polymerization reaction exergonic. D. Ribonucleoside monophosphates cannot form complementary base pairs with the DNA template. E. Ribonucleoside triphosphates are not used, rather all use deoxyriboside triphosphates. 14. How is a mutation in a bacterial cell that...
please help!!
transcription? How could the presence of a hormone in the blood have an effect on this structure? 6 points 3. What is an enhancer region and why is it important in the regulation of eukaryotic Contents Cancer Genes that cause cancer are called oncogenes. d. promoter genes. a. operator genes. b. pseudogenes.c 2A mutation in which of the following genes would be LEAST likely lead to a cancer? a. growth hormone gene b. growth hormone receptor gene c....
For Questions 4-18, consider the mutations described in the left-hand column below. Identify whether the Lac operon will be ON or OFF in each of the environments listed across the top. The expression of the normal (wild type) operon is given. Note that "ON" and "OFF" refer to whether the operon is expressed at high levels (ON) or basal//low/no levels (OFF). (Hint: mutations render the indicated site inactive while leaving the remaining part of the operon or protein functional.) Note...
Short-Answer Questions for Thought and Review 1. Describe three ways in which plasmids can increase the pathogenic nature of bacteria. 2. Explain what this statement means not always expressed as a phenotype." the information of a genotype is 3. Summarize the differences between prokaryotic and eukarytoic mRNA. 4. Explain why anticodon wobbling is useful to the cell in terms of protection against mistakes and the conservation of anabolic energy that would otherwise have to be spent manufacturing RNAs. 5. Table...
PLEASE COMPUTER TYPED* OR VERY CLEAR HANDWRITING with
details
1. Radioactive (14C) uridine (lots of it) is added to a growing culture of bacteria for 10 seconds and then the drug rifamycin is added (rifamycin blocks the initiation of transcription, but not continued elongation of RNA polymerases that have already begun transcribing). At two-minute intervals, 1 ml samples are removed and placed on ice. The bacteria are lysed (broken open) and an enzyme is added that will chew up all...
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