Homework Answers
Gene amplicfication
Generally, gene amplification would not convert into proto-oncogene.
The karyotype on the left is most likely from an advanced tumor due to its significant evidence of genetic instability.
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Which type of mutation would not typically convert a proto-oncogene, such as beta- catenin, into an...
Which of the following is a common mutation resulting in the conversion of a proto oncogene...
Which of the following is a common mutation resulting in the conversion of a proto oncogene into an oncogene? Gene fusion Deletion Frame shift TATA box mutation Which of the following is not a proto-oncogene? SRC MYC ERBB2 RB Which of the following statements about oncogenic translocations is true? Burkitt's lymphoma results from the fusion of two proto-oncogenes. A BCR-ABL fusion results in chronic mylogenous leukemia. Translocation linking MYC to an antibody promoter generates the Philadelphia chromosome. chromosomal translocations result...
3) Proto-oncogenes can be converted to oncogenes by various genetic changes. Which of these mechanisms is...
3) Proto-oncogenes can be converted to oncogenes by various genetic changes. Which of these mechanisms is not likely to contribute to conversion to an oncogene? Select one: A: Extra copies of the gene are made, thereby enhancing expression. B: A mutation occurs upstream of the gene that results in a more active promoter. C: Chromosomes break and fragments are translocated from one chromosome to another. D: Point mutations occur that result in a protein more resistant to degradation. E: All...
Please help with answers to these questions answer the ones that are straightforward like this one...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
Which of the following statements best describes the difference between a benign and malignant tumor?_____ (type...
Which of the following statements best describes the difference
between a benign and malignant tumor?_____ (type 1, 2, or 3 in the
blank)
1. benign tumors rarely interfere with organ function but
malignant tumors often impair and spread to other organs.
2. benign tumors are produced from unregulated cell growth but
malignant tumors are regulated
3. benign tumors metastasize but malignant tumors do not
Which of the following statements best describes metastasis?
____
1. metastasis is unregulated growth of cells...
please answer all 6 questions Question 27 3 pts TRBP is a protein important for the...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
QUESTION 13 Which of the following would occur if a mutation caused Kinase 1 to be...
QUESTION 13
Which of the following would occur if a mutation caused Kinase 1
to be unable to be phosphorylated? (Select all)
RTK would bind VEGF
RTK would phosphorylate itself
RAS would become active
The phosphorylation cascade would occur
The endothelial cell would divide
0.2 points
QUESTION 14
Imagine that an endothelial cell has a mutation in several of
the enzymes that perform mismatch repair. The endothelial cell
replicates its DNA and then divides into two cells. The resulting...
28 29 30 31 32 33 28. Genes found in segments of chromosome called heterochromatin would...
28
29
30
31
32
33
28. Genes found in segments of chromosome called heterochromatin would likely be expressed at high levels. expressed at low levels, or not at all. deleted before replication. maternally inherited only. none of these 29. (Use this representation to answer the following question.) DNA template strand 5 3' DNA complementary strand 3' 5' Using the double-stranded molecule above, in which direction does the RNA polymerase enzyme move? 3' → 5' along the template strand 5'...
90170021 201901/P53 pd 8. (3) Lator you find out that you have access to a microarray...
90170021 201901/P53 pd 8. (3) Lator you find out that you have access to a microarray for 10 gones that are associated with John's type of cancer. The microarray was done comparing normal tissue the microarray are shown below. One of the patients is John sequence of proteins. What are these mutations? How do the mutations change the 9. (2) If you were to suggest gene therapy to the family. how you describe what the main goal of this therapy...
need some assistance with this. thank you very much 1. Free radicals are __________ . (A)...
need some assistance with this. thank you very much 1. Free radicals are __________ . (A) molecules that have lost an electron (C) molecules with extra neutrons (B) escaped political prisoners (D) produced by vitamins 2. The chromosomal location of the APC gene was originally identified by finding a region of the genome that was _________ in patients with colorectal cancer. (A) deleted (B) rearranged (C) normal (D) unclear 3. The National Health Service of the United Kingdom (Britain) has...
need some assistance with this please. thank you very much 1. Free radicals are __________ ....
need some assistance with this please. thank you very much 1. Free radicals are __________ . (A) molecules that have lost an electron (C) molecules with extra neutrons (B) escaped political prisoners (D) produced by vitamins 2. The chromosomal location of the APC gene was originally identified by finding a region of the genome that was _________ in patients with colorectal cancer. (A) deleted (B) rearranged (C) normal (D) unclear 3. The National Health Service of the United Kingdom (Britain)...
Which of the following is a common mutation resulting in the conversion of a proto oncogene into an oncogene? Gene fusion Deletion Frame shift TATA box mutation Which of the following is not a proto-oncogene? SRC MYC ERBB2 RB Which of the following statements about oncogenic translocations is true? Burkitt's lymphoma results from the fusion of two proto-oncogenes. A BCR-ABL fusion results in chronic mylogenous leukemia. Translocation linking MYC to an antibody promoter generates the Philadelphia chromosome. chromosomal translocations result...
Please help with answers to these questions
answer the ones that are straightforward like this one
Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...
Which of the following statements best describes the difference
between a benign and malignant tumor?_____ (type 1, 2, or 3 in the
blank)
1. benign tumors rarely interfere with organ function but
malignant tumors often impair and spread to other organs.
2. benign tumors are produced from unregulated cell growth but
malignant tumors are regulated
3. benign tumors metastasize but malignant tumors do not
Which of the following statements best describes metastasis?
____
1. metastasis is unregulated growth of cells...
please answer all 6 questions
Question 27 3 pts TRBP is a protein important for the formation of the RISC complex. Which of the following would you expect in cells with null mutations in TRBP? o Reduced siRNA-mediated mRNA degradation o Increased miRNA-mediated translational repression o Increased deadenylase-mediated mRNA degradation o Reduced proteasome-mediated protein degradation D Question 28 3 pts A protein that binds to the 3' UTR of a VEGF mRNA and promotes deadenylation and uncapping is likely to:...
QUESTION 13
Which of the following would occur if a mutation caused Kinase 1
to be unable to be phosphorylated? (Select all)
RTK would bind VEGF
RTK would phosphorylate itself
RAS would become active
The phosphorylation cascade would occur
The endothelial cell would divide
0.2 points
QUESTION 14
Imagine that an endothelial cell has a mutation in several of
the enzymes that perform mismatch repair. The endothelial cell
replicates its DNA and then divides into two cells. The resulting...
28
29
30
31
32
33
28. Genes found in segments of chromosome called heterochromatin would likely be expressed at high levels. expressed at low levels, or not at all. deleted before replication. maternally inherited only. none of these 29. (Use this representation to answer the following question.) DNA template strand 5 3' DNA complementary strand 3' 5' Using the double-stranded molecule above, in which direction does the RNA polymerase enzyme move? 3' → 5' along the template strand 5'...
90170021 201901/P53 pd 8. (3) Lator you find out that you have access to a microarray for 10 gones that are associated with John's type of cancer. The microarray was done comparing normal tissue the microarray are shown below. One of the patients is John sequence of proteins. What are these mutations? How do the mutations change the 9. (2) If you were to suggest gene therapy to the family. how you describe what the main goal of this therapy...
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