Question

3) Proto-oncogenes can be converted to oncogenes by various genetic changes. Which of these mechanisms is not likely to contribute to conversion to an oncogene?

Select one:

A: Extra copies of the gene are made, thereby enhancing expression.

B: A mutation occurs upstream of the gene that results in a more active promoter.

C: Chromosomes break and fragments are translocated from one chromosome to another.

D: Point mutations occur that result in a protein more resistant to degradation.

E: All of the above are mechanisms of oncogene conversion.

Answer 1

Proto-oncogenes can be converted to oncogenes by various genetic changes. Which of these mechanisms is not likely to contribute to conversion to an oncogene?

A: Extra copies of the gene are made, thereby enhancing expression.