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How vitamin B6 is digested, absorbed and stored

How vitamin B6 is digested, absorbed and stored
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Vitamin B6 :Pyridoxine

Vitamin B6 is a group of 3 compounds Pyridoxine,pyridoxal,pyridoxamine. It is a water soluble vitamin. It is present in many fruits and vegetables but the naturally occurring form of B6 has reduced bioavailability. It is a co- enzyme for many reaction mainly protein and amino acid metabolism. Involved in transamination,decarboxylation,deamination,transsulfuration. Synthesis of niacin coenzyme NAD+ and NADP+ from tryptophan require PLP ( co enzyme )

Digestion : digestion of vitamin B6 involves splitting the vitamin,as it is bound to the protein portion of the food.

Absorption: absorption of pyridoxal phosphate and pyridoxamine phosphate requires their dephosphorylation catalyze by alkaline phosphatase. Absorption occurs in proximal jejunum and ileum of small intestine, through passive diffusion.

Transportation: circulated in blood bound to albumin . This protect it from hydrolysis.

Storage: not stored directly instead stored in the form of its coenzyme PLP Pyridoxal phosphate, mainly in liver,brain,kidney and muscle.

Excretion:excreted as 4-pyridoxic acid through urine.

Daily requirement: Adult 1.3 - 1.7mg, child 0.3 -1.0mg

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