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Infection by Streptococcus pyogenes can lead to the production of cross-reactive antibodies that cause autoimmune damage to h
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correct answer : Rheumatic fever

Rheumatic fever is an inflammatory autoimmune disease that may develop after an infection with Streptococcus pyogenes (scarlet fever). The disease can affect the heart, joints, skin, and brain. Rheumatic heart disease is caused by rheumatic fever, an inflammatory disease that can affect many connective tissues, especially in the heart, joints, skin, or brain. The heart valves can be inflamed and become scarred over time.

antibodies generated from immune response to S. pyogenes infections recognize host-specific proteins due to epitope mimicry of bacterial and host antigens and devlops autoimmune response and cause the auto immune demage to different organs of the body.

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