1st attempt Which process in solid-phase peptide synthesis is being depicted in Step 2 of the...

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1st attempt Which process in solid-phase peptide synthesis is being depicted in Step 2 of the figure below? AAZ HH NCC Resin

DCC Fmoc AA1 0 H H.N-C- Fmoc-Red DCC - Resin AA2 AA1 Repeat 18 times Fmoc-N- Fmoc AA20 АА HAN 2 E ct P20 ct & c- Resin 18 P1

Repeat 18 times Fmoc AA20 АМ CIN Iu- 10- Resin AA Amino AA2 Amino P acid 1 cd2 Protecting group 1 po Protecting o group 2

Choose one: A. Deblocking B. Coupling C. Activation D. Deprotection

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Answer 1

Answer #1

It is process of activation of second amino acid. Amino acid with protected amino group is activated at carboxylic end by DCC (Dicyclohexylcarbodiimide). So option c is correct choice of this question.

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