The function of the beta subunit is to prevent DNA polymerase III from dissociating from the template DNA strand while still allowing the polymerase to slide along DNA as replication progresses. Given this function, the alpha helices in the beta subunit are
The function of the beta subunit is to prevent DNA polymerase III from dissociating from the template DNA strand while still allowing the polymerase to slide along DNA as replication progresses. Given this function, the alpha helices in the beta subunit are
located on the inner surface and oriented parallel to the minor and major grooves of DNA. |
located on the inner surface and oriented perpendicular to the minor and major grooves of DNA. |
located on the outer surface and do not interact with DNA. |
Answer: The alpha helices in the beta subunit are located in the inner surface and are orientated perpendicular to that of major and minor grooves of DNA. The perpendicular orientation of the alpha helices helps in restricting the access of the protein to the major and minor grooves of DNA and thus facilitates sliding of the beta subunit along the DNA. Therefore, the correct option is B.
The function of the beta subunit is to prevent DNA polymerase III from dissociating from the...
The pol III beta subunit is a ring-shaped clamp that embraces
DNA in a central 35 Å hole, tethering the remainder of pol III to
the template.
Which of the following accurately describes the structure of
the DNA polymerase III beta subunit sliding clamp protein?
The pol III beta subunit is a ring-shaped clamp that embraces
DNA in a central 35 Å hole, tethering the remainder of pol III to
the template.
Which of the following accurately describes the structure...
Which aspect of the E. coli DNA replication machinery accounts for high processivity? a. The beta sliding clamp of DNA Polymerase III b. 3’-5’ exonuclease activity of DNA Polymerase I c. 5’-3’ exonuclease activity of DNA Polymerase I d. Single strand DNA binding protein (SSB) e. The core subunit of DNA Polymerase III An explanation of the solution would be greatly appreciated, thanks!
Part
A
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to the promoter of a gene so that transcription can be initiated.
The closeup shows the secondary structure of the sigma (?)
subunit, which consists of four domains. Identify the domains
labeled 1-3.
The sigma (?) subunit binds to the core RNA polymerase
enzyme. The function of this sigma factor is to recognize and bind
to...
are
these correct? I also need help with the blanks
- MATCHING (In each blank place the letter of the term in the blank next to appropriate phrase. Use letters only once you might not need all letters) repeats M. Replication - MATCHING (In each blank, the most appropria RNA polymerasel DNA polymerase RNA polymerase Il S→ 3' delta/epsilon RNA polymerase 111 3-5 exonuclease DNA polymerasel semiconservative activity DNA polymerase II short tandem DNA 5'3'exonuclease DNA polymerase III activity DNA...
Match the enzyme activity in DNA synthesis with its function. DNA pol III (_) fragments Helicase (_) Primase (_) using template strand DNA pol I (_) double helix DNA ligase (_) adds nucleotides Topoisomerase (_) primer A. anneals DNA B. relieves overwinding C. adds nucleotides D. unwinds parental E. removes RNA primer, F. adds a short RNA 10 Proofreading and repair of the DNA double helix does NOT involves a. detecting a mis-match in base pairs. b. removing the mis-match...
Fill in the blank: During chromosome replication, the _________ enzyme synthesizes short RNA primers that get extended to form the ___________ fragments. This process uses the __________ strand as the template. Type II topoisomerases such as DNA gyrase change the LINKING number of DNA in increments of ____. They use a _________ amino-acid side chain at the active site to form a ___________ linkage to the broken DNA strands. The protein core of a nucleosome consists of ___ copies each...
BIOCHEMISTRY
2points each 1. Describe the DNA helix proposed by Watson and Crisk A) The Watson and Crick DNA model contains two DNA polymer strands coiled around a B) The strands are oriented in opposite directions, from S to 3 (antiparallel), and the two C) The sugar-phosphate backbone is located on the outside. The base pairs are stacked in the common axis. strands are twisted in a right-handed coil. center of the helix and are stabilized by specific hydrogen bonds...