Question

5. What are Koch's postulates? What steps are necessary to show that a microorganism causes a specific disease? What constraints exist on using Koch's postulates for all diseases?

Answer 1

Answers are given below :-

5.

YA [Koch's Postulates Koch's postulates are four criteria that designed to set up a causative relationship between - a microbe and a disease.. : The Postulates were formulated by Robert - koch.. and Friedrich Loeffler in 1884. 1 0 The microorganism must be present in all cases of the disease. 2 The microorganism can be isolated from the diseased host- and grown in Pure culture. ③ The microorganism / pathogen hat from the Pure culture must cause the disease when inoculated into a healthy laboratory animal. Patrogen should be oreisolated from - - the 9 Then the new host.

to show that a micro- way Steps that are necessary to show that a organisms causes a specific disease ... A microorganisms should cause a specific disease when it introduce into a healthy organs I a microorganism is isolated from a dead or diseased animal. omis Ő a mio @ Then culture the microorganisms are grown in Pure - ③ Then the microorganisms should intro- duce an injected into a healthy laboratory animal. C 9 The disease is reprisduced into the laboratory mimal. - Again isolate the microorganism from the déseased animal - Again microorganisms are grown in Pure culture and observed under microscope. ② th the microorganisms are identical that show i microorganism causes a specific disease. diseased animal colony " Pure culture obserred under microscope a inject into healthy rat obserred under mieroscope a colony Pare culture dead

. • constraints of kochs postulates : : 0 B The Particular bacteria such as the one microorganisms that causes leprosy connot be grow in Pure culture in the laboratory In koch's Postulates the specific disease must be reproduced when a pure culture of the bacteria is done. 2. So, it is not applicable for all microorga- nisms. koch's postulates noot applicable for fangi and viruses,