BRAIN:
- Brain is a very sof tissue and is surrounded by a bony case
called CRANIUM, which is made up of skull bones. CRANIUM protects
the brain from injuries.
- Brain is divided into three parts-forebrain, mid brain and hind
brain. The hind brain continues as spinal cord.
The following is the digramatic representation of BRAIN.
FOREBRAIN:
- Forebrain is the largest part of the brain. This is also called
as CEREBRUM.
- A deep groove in the middle of cerebrum divides it into two
equal halves. Each half is called as CEREBRAL HEMISPHERE(Right and
Left).
- Right and Left cerebral hemispheres are connected to each other
by a bundle of axons.
- The outer portion of the cerebral hemispheres is grey in colour
and is called CEREBRAL CORTEX.
- There are several ridges(elevations) called GYRI(Gyrus in
sinular) and grooves called SULCI(Sulcus in singular) on the
surface of brain.
- They increase the surface area of cortex so that it can
accommodate more number of neurons.
- Three very deep grooves present across each cerebral hemisphere
divides into four lobes - FRONTAL, PARENTAL, TEMPORAL and OCCIPITAL
LOBES.
- Cerebrum is the highest center for controlling several
functions in the body.
- Most interesting aspect of cerebrum is that right hemisphere
controls the functions of the left side of the body and the left
hemisphere controls the functions of the right side of the
body.
- In the cerebral cortex there are centers to recieve and analyse
various informations.
- Ex: Visual(sight), auditary center(hearing), olfacory(smell),
etc.
- Cerebrum is the seat of intelligence, thinking and
judgement.
- Parts of the brain below the cerebrum are together known as
diecephalon.
- This portion of the brain has centers that control emotions
such as anger, pain and pleasure.
- This portion also connects the forebrain with mid brain.
- Hypothalamus present in this section of brain secretes
harmones.
- Pitutary which is endocrine gland is attatched to a hypthalamus
by a stalk.
- Hypothalamus also has centres for regulating body temperature,
hunger thirst and emotions. It also secretes harmones.
MID
BRAIN:
- The mid brain consists of groups of nerve cells and a large
number of myelinated axons of the nerve cells present in other
regions of the brain.
- Some of the nervecells in this region control the body muscles
and their movements.
HIND
BRAIN:
- Hind brain consists of two parts - CERBELLUM and BRAIN
STEM.
- Cerebellum lies behind the cerebrum and has grey matter on the
surface of the white matter in the deeper layers.
- Cerebellum controls all the voluntary movements of the body. It
is also responsible for the maintenance of equlibrium and posture
of the body.
- Brain stem has two parts - PONS VAROLI and MEDULLA
OBLONGATA.
- The later continues as Spinal cord and medulla oblongata the
white matter is on the surface and the grey matter is the deeper
layers.
- Medulla oblongata has centres to control several vital
functions of the body such as respiration, heart beat, blood
pressure, secretion by salivary glands, etc.
- Medulla oblongata continues as Spinal cord. All the nerve
fibers from brain pass through Medulla Oblongata into spinal
cord.
Other important parts of the brain
CEREBROSPINAL
FLUID (CSF):
- The cerebrospinal fluid (CSF) is a clear, watery liquid that
surrounds, cushions and protects the brain and spinal cord.
- The CSF also carries nutrients from the blood to, and removes
waste products from, the brain. It circulates through chambers
called ventricles and over the surface of the brain and spinal
cord.
- The brain controls the level of CSF in the body.
MENINGES:
The brain and spinal cord are covered and protected by 3 thin
layers of tissue (membranes) called the meninges:
- dura mater – thickest outer layer
- arachnoid layer – middle, thin membrane
- pia mater – inner, thin membrane
CSF flows in the space between the arachnoid layer and the pia
mater. This space is called the subarachnoid space.
- The tentorium is a flap made of
a fold in the meninges. It separates the cerebrum from the
cerebellum.
- The supratentorial area of the brain is the area above the
tentorium. It contains the cerebrum, the first and second (lateral)
ventricles, the third ventricle, and glands and structures in the
centre of the brain.
- The infratentorial area is located at the back of the brain
below the tentorium. It contains the cerebellum and brain stem.
This area is also called the posterior fossa.
CORPUS
COLLASUM:
The corpus callosum is a bundle of nerve fibres between the 2
cerebral hemispheres. It connects and allows communication between
both hemispheres.
THALAMUS:
The thalamus is a structure in the middle of the brain that has
2 lobes or sections. It acts as a relay station for almost all
information that comes and goes between the brain and the rest of
the nervous system in the body.
HYPOTHALAMUS:
- The hypothalamus is a small structure in the middle of the
brain below the thalamus. It plays a part in controlling body
temperature, hormone.
- A substance that regulates specific body functions, such as
metabolism, growth and reproduction. secretion, blood pressure,
emotions, appetite, and sleep patterns.
PITUITARY
GLAND:
- The pituitary gland is a small, pea-sized organ in the centre
of the brain. It is attached to the hypothalamus and makes a number
of different hormones that affect other glands of the body’s
endocrine system.
- The group of glands and cells in the body that make and release
hormones (which control many functions such as growth,
reproduction, sleep, hunger and metabolism) into the blood.. It
receives messages from the hypothalamus and releases hormones that
control the thyroid and adrenal gland, as well as growth and
physical and sexual development.
VENTRICLES:
The ventricles are fluid-filled spaces (cavities) within the
brain. There are 4 ventricles:
- The first and second ventricles are in the cerebral
hemispheres. They are called lateral ventricles.
- The third ventricle is in the centre of the brain, surrounded
by the thalamus and hypothalamus.
- The fourth ventricle is at the back of the brain between the
brain stem and the cerebellum.
- The ventricles are connected to each other by a series of
tubes. The fluid in the ventricles is cerebrospinal fluid (CSF).
The CSF flows through the ventricles, around the brain in the space
between the layers of the meninges (subarachnoid space) and down
the spinal cord.
PINEAL
GLAND:
The pineal gland is a very small gland in the third ventricle of
the brain. It produces the hormone melatonin, which influences
sleeping and waking patterns and sexual development.
CHOROID
PLEXUS:
The choroid plexus is a small organ in the ventricles that makes
CSF.
CRANIAL
NERVES:
There are 12 pairs of cranial nerves that perform specific
functions in the head and neck area. The first pair starts in the
cerebrum, while the other 11 pairs start in the brain stem. Cranial
nerves are indicated by number (Roman numeral) or name.
Cranial nerves and their functions
- olfactory - smell
- optic - vision and light detection by
the pupil
- oculomotor - eye movement upward,
downward or inward narrowing and widening of the pupil lifting of
the eyelid
- trochlear - eye movement downward and
inward
- trigeminal - facial sensation
chewing
- abducens - outward eye movement
- facial - facial expression closing of
the eyelid taste in the front part of the tongue
- acoustic - hearing balance
- glossopharyngeal - swallowing gag
reflex speech
- vagus - swallowing gag reflex speech
(vocal cords) control of muscles in internal organs
- accessory - neck turning shoulder
shrugging
- hypoglossal - tongue movement
BLOOD-BRAIN
BARRIER:
- The blood-brain barrier is a specialized system of blood
vessels and enzymes.
- A protein that speeds up certain chemical reactions in the
body. that protect the brain from chemicals or toxins produced by
bacteria. It helps maintain a constant environment for the
brain.
- The blood-brain barrier is made up of very small blood vessels
(capillaries) that are lined with thin, flat endothelial cells. In
other parts of the body, endothelial cells have small spaces
between them that allow substances to move in and out of the
capillary so they can reach other cells and tissues. In the brain,
the endothelial cells are packed tightly together so substances
cannot pass out of the bloodstream into the brain. The enzymes also
restrict the types of substances that can be carried from the
bloodstream into the brain.
- Some substances can pass through the blood-brain barrier, such
as very small molecules and molecules that can be dissolved in fat
(are lipid soluble).
Types of cells in the
brain
The brain is made up of neurons and glial cells:
NEURONS:
- These cells carry the signals that make the nervous system
work.
- They cannot be replaced or repaired if they are damaged.
- glial cells (neuroglial cells)
- These cells support, feed and protect the neurons.
The different types of glial cells are:
- astrocytes
- oligodendrocytes
- ependymal cells
- microglial cells
entricles FOREBRAIN Cerebrum rpus callosum Thalamus Hypothalamu Pituitary gland Cerebellum Pons HINDBRAIN Medulla Brain stem