Question

Graded Homework Set 6 8 pts due first 5 min of rec 10/09/17 name recitation section B-oxidation is the major pathway for oxidizing fatty acids (components of lipids). A sequence of small chemical changes results in removing a two-carbon "bite" from the hydrocarbon chain. The "bite" (acetyl CoA) is then carried to Krebs' cycle to complete the oxidation of the carbons to CO2. 1. What type of reaction is happening to the hydrocarbon chain? Show both names: Which form of the coenzyme is more reduced, FAD or FADH2? Which form of the coenzyme stores more energy, FAD or FADH2? 2. Reaction 2 is what type of reaction? 3. What type of reaction is happening to the hydrocarbon chain? Show both names: NAD Which form of the coenzyme is more reduced, NAD or NADH? H2 Which form of the coenzyme stores more energy,? NAD or NADH Coenzyme A-SH 4. Notice that enzymes break one specific C-C bond in this reaction (difficult for chemists to do this in the lab!) 5. The two carbon "bite" is carried to Krebs' Cycle The remaining four-carbon piece returns to the first enzyme in this pathway and goes through the same series of rxns to remove another two carbon "bite". What is the fate of the two carbon "bite"?

Answer 1

1) Dehydrogenation or Oxidation

FADH2 is more reduced and it stores more energy

2) Hydration

3) Dehydrogenation or Oxidation

NADH is the more reduced form and have high energy

4)Acetyl-CoA is oxidised into CO2 and water in kerb cycle.