Question

A male mouse from a true-breeding strain of hyperactive animals is crossed with a female mouse from a true-breeding strain of lethargic animals. (These are both hypothetical strains.) All the progeny are lethargic. In the F2 generation, all offspring are lethargic.

What is the best genetic explanation for these observations?

recessive then a If the lethargic gene is the F2 progeny would be immediate progeny. may be involved. In that case, some of lethargic because maternal effects are temporary, affecting only the maternal effect dominant mitochondrial defect If the lethargic condition is caused by then perhaps injection experiments could be used some infective agent If the lethargic condition is caused by a then the condition would persist in all offspring hyperactive mothers, through more than one generation of

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Answer #1

If lethargic gene is Recessive , then a Maternal effect may be involved. In that case, some of the F2 progeny would be Hyperactive because maternal effects are temporary, affecting only the immediate progeny.

If the lethargic condition is caused by Some infective agent, then perhaps injection experiments could be used.

If the lethargic condition is caused by a Mitochondrial defect , then the condition would persist in all offspring of Lethargic mothers, through more than one generation.

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