Question

13. Which of these statements about elongation factors is true? (A) EF-Ts binds GTFP (C) EF-Ts is a GTPase (D) EF-G doesnt bind to GTP (B) EF-G is a GTPase 14. Which of these is NOT a proofreading mechanism for translation elongation? (A) tRNA accomodation (B) Ribosome 16S rRNA (C) EF-G GTP hydrolysis (D) EF-Tu GTP hydrolysis
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Answer #1

Question 13: The correct answer is (B) EF-G is a GTPase.

Explanation: In the translation elongation, the movements of mRNA and tRNA are coordinated within the ribosome. These movements are collectively called as translocation. The GTPase activity of EF-G involves the completion of the translocation while EF-Ts acts as a GTP exchange factor for EF-Tu.

Question 14: The correct answer is (C) EF-G GTP hydrolysis.

Explanation: The ribosome uses minor groove interaction, GTPase activity of EF-Tu, and t-RNA accommodation to select against incorrect aminoacyl-tRNAs. Minor groove interaction involves two adjacent adenine residues in the 16S rRNA component. Whereas the GTPase activity of EF-G involves the completion of the translocation.

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