Question

Choose the correct answers for the following questions. Also explain the biology behind why answers are scientifically accurate. L.If' a single point mutation occurs at a random place in the genome, what is the most likely outcome? 1. The mutation will have a noticeable negative effect on the organism. 2. Th 3. The mutation will lead to a noticeable gain-of-function in a agene 4. The mutation will have a noticeable positive effect on the organism 5. The mutation will have no noticeable effect on the organism. e mutation will lead to a noticeable loss-of-function in a gene. 2. You have 23 pairs of chromosomes in your somatic cells. Each homologous pair is comprised of one chromosome from your mother and one from your father. What are the chances of making a gamete (sperm cell or egg cell) in which all of the chromosomes are from your father? For this question, assume that there is no meiotic crossing-over. c, 1/223 d.1/240 92 е. 112 a. 1/24 b. 1/214

Answer 1

Option 5 is the answer. A single point mutation in a random place in the genome is highly unlikely to cause any noticeable effect on the organism because in most cases, these mutations are likely to be recognized and repaired by DNA repair mechanisms. Hence, single DNA mutations in the genome of a single cell of a fully developed organism will not cause much effect.

The chances of you making a gamete with all chromosomes from your father would be almost impossible in real life due to meiotic recombination. Since the question assumes no meiotic crossing over, in your gametes there is a probability of 1/2 of each chromosome coming from your father. Since there are 23 pairs of chromosomes, the probability of all your chromosomes being from your father is 1/2²³.