explain the behaviour of the three types of amines toward acetic anhydride. Why wont tertiary amines react with acetic anhydride?
explain the behaviour of the three types of amines toward acetic anhydride. Why wont tertiary amines...
Explain why primary and secondary amines form hydrogen bonds but tertiary amines do not?
Question 1: draw a mechanism for each of the reactions. Explain why the different amines create different products. Question 2: Explain the product distribution. primary vs. secondary or tertiary amines and their corresponding products. 1. Draw a mechanism for each of the transformations (primary and secondary amines). Explain why the two different amines lead to different molecules. NaOH RNH2 + CHCI 1° amine R-NEC RNH + CHCI- 2º amine HNR2 2. What are some likely reasons that contribute to this...
H3PO4 OH + OH OH salicylic acid acetic anhydride acetic acid acetylsalicylic acid (aspirin) 1. Why is it better to perform acetylation with acetic anhydride rather than using a Fischer esterification with acetic acid? 2. Draw a complete arrow-pushing mechanism for the reaction. 3. When an old sample of aspirin is left in moist conditions, it will begin to smell like vinegar. Draw a reaction scheme and briefly explain what happened.
provide a mechanism for both of the reactions provided. why can secondary or tertiary amines not be formed using this reaction? 1. Complete a mechanism for both pathways below, the hydrolysis (use acidic or basic conditions - note which is used) and the Ing- Manske procedure. Provide intermediates with arrows for each step. H2O .COH + RNH2 Hoor HO "co₂H oa aq. H2NNH2 2. Why can this reaction only form 1 (primary) amines, not 2 (secondary) or 3 (tertiary)?
please answer questions 1, 2, 3, and 4. thank you. Amines 257 Questions 1. Explain the purpose of the following in this experiment: a. acetic acid b. water in step 4) c. charcoal. 2. Why is acetic anhydride a better acylating agent than acetic acid? 3. Acylations are often carried out in the presence of a base, such as a 3 amine or pyridine. What is the function of the base in these reactions? 4. Monoacylation of a primary amine...
4. Explain why maleic anhydride is exceptionally reactive and why anthracene is usually unreactive. Explain why did this Diels-Alder reaction proceed? Why does anthracene react from the central ring system and not one of the outer rings?
Explain why treatment of a preparation of E. coli single strand binding protein (SSB) with acetic anhydride produces a chemically modified protein that is unable to bind to DNA. [Hint: Acetic anhydride reacts with primary amino groups. Which amino acids would that include, and what would be the consequence of the reaction?] 3. Explain why treatment of a preparation of E. coli single strand binding protein (SSB) with acetic anhydride produces a chemically modified protein that is unable to bind...
4. Why don't tertiary halides react with nucleophiles via an SN2 prod 5. For a chiral tertiary substrate, would the chirality be preserved in an SN1 reaction? Explain. 6. Aside from tertiary alcohols, what other types of compounds will readily undergo substitution via an SN1 process? Why?
0.203 gram of salicylic acid, and 0.658 mL of acetic anhydride (d = 1.082g/mL) react in the presence of an acid catalyst to produce acetylsalicylic acid. Determine the limiting reagent and then calculate the theoretical yield of the product in grams. Report the theoretical yield to three decimal places.
Is this reaction Sn1 or Sn2? Why? HN CH anline CBH N 93.13 g/mol acetic anhydride CHENO 102.09 acetanilide CHNO 135.16 acetic acid C3H402 60.05