What happens to gram (+) and (-) bacteria at the end of the classical complement cascade?

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What happens to gram (+) and (-) bacteria at the end of the classical complement cascade?

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Answer 1

Answer #1

Classical complement cascade is activated by the Antigen-antibody complexes which causes activation of C1 which culminates in the activation of C3 to form C3 convertase.

Then complement cascade end at the formation of MAC (Membrane Attack Complexes).

This complement cascade generates the opsonins such as C3b which binds he to bacteria facilitating their phagocytosis.

MAC helps to kill these bacteria directly by the acting on the membrane, creating pores in the membrane, rendering the cell to get lysed.

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Answer 2

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What happens to gram (+) and (-) bacteria at the end of the classical complement cascade?

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for the three pathways for complement activation (alternative, lectin, and classical), which pathway is the least...

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