1.What can we conclude about the expression of alkaline phosphatase in pork and liver tissues?Is alkaline phosphatase expressed in all tissues? In equal amounts?
2.Are there any problems that might make one tissue more difficult to examine than an other?
3.Why do you think the enzyme is expressed in the cells that it is?
4.Is the expression of the enzyme localized in any particular areas of the tissues? Is it all over? How can you tell?
1. Alkaline phosphate(ALP) is an enzyme that removes phosphate groups from biomolecules. Pork alkaline phosphatase (which represents muscle) and liver ALP are two different isoforms of the same enzyme
It is a 86 kilo dalton protein that is expressed in all the tissues throughout the body. However its expression is more in tissues such as liver kidney, mucosa of intestine, bones, placenta.
1.What can we conclude about the expression of alkaline phosphatase in pork and liver tissues?Is alkaline...
1. What can you conclude about a patient exhibiting both hemoglobinemia and hemoglobinuria with respect to where his red blood cells are being destroyed? 2. Why would you predict that incorrect lysis of red blood cells in areas or organs that normally don’t break them down would result in jaundice? 3. You examine blood from a patient that you believe has some form of anemia. Interestingly, you establish that his neutrophils have normal nuclei but the red blood cells can...
What control elements regulate expression of the mPGES-1 gene? The promoter of a gene includes the DNA immediately upstream of the transcription start site, but expression of the gene can also be affected by control elements. These can be thousands of base pairs upstream of the promoter, grouped in an enhancer. Because the distance and spacing of these control elements make them difficult to identify, scientists begin by deleting sections of DNA that contain possible control elements and measuring the...
26. Why did Jessie’s carnitine deficiency cause her to have abnormally low plasma glucose levels at the end of a fasting study, when compared to a healthy person who has fasted for the same length of time? In the absence of carnitine, the liver stores large amounts of glycogen; absorption of glucose to create these stores depletes blood glucose Carnitine acts as a hormone and stimulates glucose release from the liver; lack of carnitine results in loss of hepatic glucose...
Developmental Biology Help! Please answer all the questions 1) We discussed the fact that each stripe expression pattern is affected by the enhancer region that is utilized. Knowing that the maternal genes and the gap genes can both contribute to the pair-rule genes, and that in many cases multiple stripes may be contained in one area of GAP, how does the embryo have definition of stripes if all of these transcription factors can be within the same cell A it...
QUESTION 1 Although SARS-CoV-2 is currently a global health threat, how might we turn it into a tool for biotechnology? a. It could possibly be turned into a viral vector against lung cancers b. Its promoters might be used to express genes in lung cells c. Its surface proteins could be used for new epitope tags d. All of the above QUESTION 2 Which of the following are applications of molecular assembly described in this course? a. It can be...
Then sheer speed with which end-stage liver failure can consume a patient is what makes the disease so devastating.1,2 Unfortunately, Ms. S.’s family had never been informed about that reality. When they brought her in for a mere urinary tract infection, they were shocked that it took only days for her heart, lungs, and immune system to fail alongside her liver. Her family waited in hopeful anticipation for Ms. S.’s condition to take a turn for the better, and therefore...
the sheer speed with which end-stage liver failure can consume a patient is what makes the disease so devastating.1,2 Unfortunately, Ms. S.’s family had never been informed about that reality. When they brought her in for a mere urinary tract infection, they were shocked that it took only days for her heart, lungs, and immune system to fail alongside her liver. Her family waited in hopeful anticipation for Ms. S.’s condition to take a turn for the better, and therefore...
the sheer speed with which end-stage liver failure can consume a patient is what makes the disease so devastating.1,2 Unfortunately, Ms. S.’s family had never been informed about that reality. When they brought her in for a mere urinary tract infection, they were shocked that it took only days for her heart, lungs, and immune system to fail alongside her liver. Her family waited in hopeful anticipation for Ms. S.’s condition to take a turn for the better, and therefore...
sheer speed with which end-stage liver failure can consume a patient is what makes the disease so devastating.1,2 Unfortunately, Ms. S.’s family had never been informed about that reality. When they brought her in for a mere urinary tract infection, they were shocked that it took only days for her heart, lungs, and immune system to fail alongside her liver. Her family waited in hopeful anticipation for Ms. S.’s condition to take a turn for the better, and therefore repeatedly...
The sheer speed with which end-stage liver failure can consume a patient is what makes the disease so devastating.1,2 Unfortunately, Ms. S.’s family had never been informed about that reality. When they brought her in for a mere urinary tract infection, they were shocked that it took only days for her heart, lungs, and immune system to fail alongside her liver. Her family waited in hopeful anticipation for Ms. S.’s condition to take a turn for the better, and therefore...