Question

When there are too many red blood cells, is the bohr effect still observed?

Answer 1

Bohr effect refers to the shift in the oxygen dissociation curve caused by changes in the concentration of carbon dioxide or the pH of the environment. It is the increase in the carbon dioxide partial pressure of blood or decreases in blood pH resulting in a lower affinity of hemoglobin for oxygen. Therefore, in the presence of high red blood cells, high hemoglobin content is already present which ensures proper binding of Hb to the oxygen molecules, which is the opposite of what happens in the Bohr effect. Thus, no Bohr effect is observed in the presence of high red blood cells.