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All of the following can cause flaccid paralysis EXCEPT: A. Neuro-muscular Blocking Agents B. poliomyelitis C....

All of the following can cause flaccid paralysis EXCEPT:

A. Neuro-muscular Blocking Agents

B. poliomyelitis

C. myasthenia gravis

D. Acetylcholinesterase Inhibitors

E. botulism

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Answer #1

D. Acetylcholinesterase Inhibitors

Flaccid paralysis, regardless of cause is the inability of muscles to respond to nerve signalling mediated by Acetylcholine receptors. The lack of this signaling leads to poor muscle function. All of the examples above interfere with muscle function and lead to flaccid paralysis. However, Acetylcholine-esterase inhibitors lead to the accumulation of acetylcholine in the neuromuscular junctions, thereby promoting the firing of muscles. Therefore, Acetylcholine-esterase inhibitors cannot be causative agents for flaccid paralysis since they promote the opposite effect.

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