Which of the following agents can cause tissue necrosis that may increase in size and depth...

Question

Question

Answer 1

Answer #1

Doxorubicin is a chemotherapy drug which has various side effects like

1) Bone marrow suppression

2) Cardiotoxic

3) Oral ulcers

4) Alopecia

5) Tissue necrosis or extravasation.

Doxorubicin is used in treatment of various cancers like

1) Breast cancer

2) AML and ALL

3) Gastric cancer

4) Ovarian cancer

Doxorubicin acts by inhibiting topoisomerase enzyme which helps in unwinding of DNA for transcription.

So, among the four options, Doxorubicin is the answer.

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Answer 2

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