Gene therapy to treat RPE65-mediated RP is administered via ________ injection, while gene therapy to treat...
Gene therapy to treat RPE65-mediated RP is administered via ________ injection, while gene therapy to treat LHON is administered as an intravitreal injection.
Homework Answers
Leber congenital amaurosis (LCA) is caused by mutations in the
RPE65 gene.
Gene therapy for LCA uses a subretinal injection of
Adeno-associated viral vectors to deliver the functional copy of
the RPE65 cDNA to the retinal pigment epithelial cells of the
patient.
Gene therapy to treat RPE65-mediated RP is administered via
SUB-RETINAL injection, while gene therapy to treat
LHON is administered as an intravitreal injection.
Add Answer to:
Gene therapy to treat RPE65-mediated RP is administered via
________ injection, while gene therapy to treat...
1. Gene therapy involves inserting a functional copy of a gene into the genome to treat...
1. Gene therapy involves inserting a functional copy of a gene into the genome to treat or prevent disease. However, in reality this process is not as easy as it sounds. What were some challenges the researchers faced as they tried to develop a gene therapy to treat Leber Congenital Amaurosis (LCA)? 2. Luxturna gene therapy officially costs $425,000 per eye ($850,000 for both eyes). Do you think that this is an appropriate price for this treatment?
A transgenic plant was constructed by introducing a fungal gene via Agrobacterium mediated transformation. The gene...
A transgenic plant was constructed by introducing a fungal gene via Agrobacterium mediated transformation. The gene was isolated from the fungus Aspergillus niger and encodes for biosynthesis of a metabolite that enhances plant growth. The gene is not present in wild type plants. However, the transgenic plants do not have the expected phenotypes. How are you going to 60 demonstrate that the fungus gene is present in those plants, despite the lack of a phenotype?
A 17-ml dose of ferumoxytol is administered via an intravenous injection. If the concentration of elemental iron in the...
A 17-ml dose of ferumoxytol is administered via an intravenous injection. If the concentration of elemental iron in the solution is 30 mg/ml, how much iron is delivered in one dose?
A 17-ml dose of ferumoxytol is administered via an intravenous injection. if the concentration of elemental iron in the...
A 17-ml dose of ferumoxytol is administered via an intravenous injection. if the concentration of elemental iron in the solution is 30 mg/ml, how much iron is delivered in one dose.
A dose of cyanocobalamin (vitamin B12) is administered via an intramuscular or deep subcutaneous injection. A typical do...
A dose of cyanocobalamin (vitamin B12) is administered via an intramuscular or deep subcutaneous injection. A typical dose is 0.1 mg/day. If the concentration of the cyanocobalamin solution is 1 mg/ml, and each vial contains 1 ml of the solution, how many days’ dose would be provided by 5 vials?
A dose of cyanocobalamin (vitamin B12) is administered via intramuscular or deep subcutaneous injection. A typical dose...
A dose of cyanocobalamin (vitamin B12) is administered via intramuscular or deep subcutaneous injection. A typical dose is 0.1 mg/day. If the concentration of the cyanocobalamin solution is 1 mg/ml, and each vial contains 1 ml of the solution, how many days' dose would be provided by 5 vials?
Estradiol valerate is an estrogen drug used to treat menopausal vasomotor symptoms. A typical dose, administered...
Estradiol valerate is an estrogen drug used to treat menopausal vasomotor symptoms. A typical dose, administered by deep IM injection, consists of 20 mg once every four weeks. If a vial of estradiol valerate contains 5 ml with a concentration of 10 mg/ml, how many vials will be needed for 40 weeks of therapy? Follitropin alfa is a fertility drug that stimulates follicle maturation and induces ovulation. A typical dose consists of subcutaneous injections of 75 units/day for 14 days....
Quinidine, a moderate sodium channel blocker used to treat arrhythmias, can be administered in one of...
Quinidine, a moderate sodium channel blocker used to treat arrhythmias, can be administered in one of two common forms: quinidine sulfate and quinidine gluconate. In the form of quinidine gluconate, a dose can be administered by injection. If the concentration of the solution is 80 mg/ml, how many milliliters of quinidine gluconate will be required for a dose of 800 mg?
Gene therapy is not necessarily a new technology, but it is technology that may finally make...
Gene therapy is not necessarily a new technology, but it is technology that may finally make a contribution to human health. Create an initial post to this discussion where you argue both for and against the promotion of gene therapy as a viable option to treat genetic disease.
Calcium chloride is used to treat disprders arising from low levels of calcium in the blood...
Calcium chloride is used to treat disprders arising from low levels of calcium in the blood plasma. A typical adult dose is 500 mg/day administered from 1 to 3 days. The dose of medicine is delivered via a slow intravenous injection. If the injection takes 5 minutes to deliever the drug, what is the dosage rate in milligrams per minute?
Most questions answered within 3 hours.
-
Do not neglect the old for the new. The existing business must
not lose priority simply...
asked 2 hours ago -
Kylie is a single mom with two dependent children,
Tanner, age 7 and Olivia, age 11....
asked 3 hours ago -
Phosphorous + bromine = phosphorous tribromide. If 35.0 g of
bromine are reacted and 27.9 grams...
asked 5 hours ago -
Derive the long wavelength limit of the Planck energy density
distribution
asked 5 hours ago -
Calculate the pH of each of the following solutions.
0.50 M HBr
3.1×10−4 M KOH
4.2×10−5...
asked 8 hours ago -
For the year ended December 31, Depot Max’s cost of merchandise
sold was $85,600. Inventory at the...
asked 8 hours ago -
Week 10 - Professional Memo Assignment
Professional Memo Assignment
Your mission for this week, should you...
asked 8 hours ago -
Write a Python program that stores the data for each
player on the team, and it...
asked 8 hours ago -
In
the last 3 months, mike never knows when he is going to get his
allowance...
asked 9 hours ago -
Is Ca(OH)2 a Bronsted base, Lewis base, or both? Why?
asked 9 hours ago -
1A- Why don’t voters complain about U.S. tariffs on imported
sugar?
Because sugar is only a...
asked 9 hours ago -
Cash Payback Period
Primera Banco is evaluating two capital investment proposals for
a drive-up ATM kiosk,...
asked 9 hours ago