What would be the likely result of activation of telomerase in somatic cells? A) immediate cell...
What would be the likely result of activation of telomerase in somatic cells?
A) immediate cell death
B) Nothing, as somatic cells already have active telomeres
C) Cells capable of continuous division
D) premature aging of the cell
E) Cells displaying extensive DNA rearrangement and mutation
Homework Answers
C) Cells capable of continuous division.
Telomerase helps in the elongation of telomeres which helps in cell division.
Normally somatic cells don't have active telomerase enzyme. When there is an activation of telomerase that causes continuous division of the cells i.e. they become cancer cells and this continuous division leads to the formation of tumours in a healthy person.
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Match the following phenotypes with the mutation that would be the most likely to be its cause. The mutant proteins are listed below, followed by the protein domain that is mutated in each case, followed by the amino acid change that is a result of the mutation Try to answer each question by using the following reasoning: if you observe a phenotype, then that could be due to a mutation in protein in which the domain has had an amino...
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SOMATIC HYPERMUTATION (Figures 7 and 8). Indeed, the discovery of AID provided the missing MSH2-deficient mice had previously been taken to indicate that somatic mutation is initiated by diversification at C:G pairs with MSH2-mediated recognition then triggering a subsequent stage of diversification at A:T pairs. Such a two-stage model was supportedations by the observation that CG-biased mutation was also a characteristic of somatic mutation in B-c nes9 and...
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