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Billirubin is conjugated in the liver by addition of two molecules to increase its solubility, what...

Billirubin is conjugated in the liver by addition of two molecules to increase its solubility, what are the two molecules?

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Answer #1

Billirubin is transported within the hepatocyte to the smooth Endoplasmic reticulum , where its carboxyl groups are conjugated with glucuronic acid which catalyzed bu enzyme uridine diphosphate glucouronosyltransferase (UDPGT-1)

Bilirubin conjugated with glucuronic acid also binds to albumin.

So, 2 molecules are glucuronic acid and albumin.

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