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A major difficulty in preparing vaccines against viral diseases in the rapidity with which the virus...

A major difficulty in preparing vaccines against viral diseases in the rapidity with which the virus mutates to vaccine resistance. what is the likely mechanism for this hypermutability? would you expect this problem to affect DNA and RNA viruses equally? please explain.

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Answer #1

Hello,

Mutation may occur because after replication their may not be any proofreading of the newly replicated genome.However,Mutation rate is different in DNA viruses and RNA viruses.Mutation rate is slow in DNA viruses as DNA replication is followed by proof reading but since RNA replication is not followed by proofreading they mutate at much faster rate.

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