Question

Which one of the following conditions would increase the synthesis of fatty acids?

a. A decrease in the insulin/glucagon ratio

b. A decrease in the levels of cytosolic citrate

c. An increase in the activity of the carnitine shuttle

d. a decrease level of malonyl-SCoA

e. A decreased activity of isocitrate dehydrogenase

I keep researching this questions and end up with concluding that none of the choices are right. Please help thanks.

Answer 1

A. A decrease in insulin/glucagon ratio.

The insulin and glucagon has an indirect effect on the synthesis of fatty acids The insulin glucagon ratio is said to control carbohydrate and lipid metabolism. The insulin is anabolic whereas glucagon acts as a catabolic hormone. The decrease in the insulin - glucagon ratio leads to stimulation of nutrients. It also promotes gluconeogenesis and glycogenesis leading to synthesis of fatty acids and glycerol from the adipose tissues for energy. Therefore,also loosing excess weight (ketogenesis).

Hope this helps you. All the best!:)