What happens to a protein that doesn't have a signal sequence?
A. It is secreted from the cell.
B. It remains in the cytosol
C. It gets degraded in the lysosome.
D. It becomes a plasma membrane protein.
Ans.
B. It remains in the cytosol.
Explanation :-
Proteins are compiled and fed into ER during translation if they have an amino sequence or also called signal sequence i.e Signal peptide. Basically proteins bound for organelles in the endomembrane system like Golgi apparatus, lysosome etc. enter the ER. Proteins that don't have signal sequence or signal peptide remain in the cytosol for the rest of translation.
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