The following results represent the oxygen binding activity of purified myoglobin,
purified hemoglobin, and hemoglobin in human blood cells.
pO2 (Torr) |
Fraction of purified myoglobin with O2 |
pO2 (Torr) |
Fraction of purified hemoglobin with O2 |
pO2 (Torr) |
Fraction of hemoglobin in red blood cells with O2 |
0.5 |
0.161 |
0.1 |
.00315 |
10.6 |
0.10 |
1.0 |
0.277 |
0.35 |
.0099 |
19.5 |
0.30 |
2.0 |
0.434 |
0.794 |
.0306 |
27.4 |
0.50 |
3.0 |
0.535 |
1.748 |
.0909 |
37.5 |
0.70 |
4.0 |
0.605 |
2.884 |
.24 |
50.4 |
0.85 |
6.0 |
0.697 |
4.467 |
.50 |
77.3 |
0.96 |
8.0 |
0.754 |
5.75 |
.76 |
92.3 |
0.98 |
12 |
0.821 |
7.94 |
.909 |
||
20 |
0.885 |
12.88 |
.969 |
||
29.51 |
.99 |
||||
67.60 |
.997 |
Based on the data shown in the Table, determine the Hill coefficients of purified myoglobin, purified hemoglobin, and hemoglobin in red blood cells.
Answer:
For purified Mayoglobin the Hill cofficient is-
For purified Heamoglobin the Hill cofficient is-
For purified Heamoglobin in blood the Hill cofficient is-
n>1 describes positive cooperativity ( 1 ligand binding faciliates other)
n<1 describes negative cooperativity (1 ligand binding inhibits other binding)
Please Rate My Answer....... Thank......u...
The following results represent the oxygen binding activity of purified myoglobin, purified hemoglobin, and hemoglobin in...