Describe the nature of a ligand-receptor interactionand state how such interactions initiate a signal-transduction system
- Describe the nature of a ligand-receptor interactionand state how such interactions initiate a signal-transduction system
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Describe the nature of a ligand-receptor
interactionand state how such interactions initiate a
signal-transduction system
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a...
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a realistic signal transduction cascade, that eventually leads to the transcription of the GRAD gene. The GRAD protein is secreted by the cell. Describe the critical steps in gene transcription, RNA processing and in translation, and which structures and organelles are involved. Include: organelles involved, transcription factors, amplification, RNA polymerase, a signal transduction cascade, ribosomes, how the signal reaches the nucleus, secretion from the cell...
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a...
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a hypothetical but realistic signal transduction cascade, that eventually leads to the transcription of the GRAD gene. The GRAD protein is secreted by the cell. Describe the critical steps in gene transcription, RNA processing and in translation, and which structures and organelles are involved. A detailed description of transcription and translation, and all proteins involved, is NOT expected, but a description of the main steps...
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a...
In a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a hypothetical but realistic signal transduction cascade, that eventually leads to the transcription of the GRAD gene. The GRAD protein is secreted by the cell. Describe the critical steps in gene transcription, RNA processing and in translation, and which structures and organelles are involved. A detailed description of transcription and translation, and all proteins involved, is NOT expected, but a description of the main steps...
in a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a...
in a eukaryotic cell, the hydrophilic ligand CUE binds the enzyme-linked receptor CUE receptor. Describe a hypothetical but realistic signal transduction cascade, that eventually leads to the transcription of the GRAD gene. The GRAD protein is secreted by the cell. Describe the critical steps in gene transcription, RNA processing and in translation, and which structures and organelles are involved.
A) Draw and describe the Wnt signal transduction pathway i) with and ii) without ligand binding. ...
A) Draw and describe the Wnt signal transduction pathway i) with and ii) without ligand binding. Follow the molecules from the receptor, all the way into the nucleus. B) Summarize the formation of the dorsal axis in the Xenopus embryo beginning with the oocyte and proceeding through to the late blastula. Indicate where Wnt signaling is and is not activated. C) Explain the changes in gene expression that occur after Wnt activation and how these affect organizer genes and gastrulation....
Describe how the signal transduction pathway that involves G proteins is similar to the signal transduction...
Describe how the signal transduction pathway that involves G proteins is similar to the signal transduction pathway involving inositol triphosphate. In a second paragraph describe how these 2 signal transduction pathways differ from one another. In a third paragraph describe how these 2 pathways are turned off.
MEK is second messenger. Second messengers transmit and amplify the signal received by receptor –ligand interactions...
MEK is second messenger. Second messengers transmit and amplify the signal received by receptor –ligand interactions on the outside of the cell. Assume that the cancer cell has a mutation causing a constitutively active MEK (on all the time). Design a drug that acts as either a competitive inhibitor, allosteric inhibitor, or antagonist that would specifically inhibit this phenotype. Explain the Kd/Km of your drug for your chosen target. Explain the type of inhibition you will use. Explain how your...
Signal amplification is an essential step in signal transduction. Which of the following steps of signal...
Signal amplification is an essential step in signal transduction. Which of the following steps of signal transduction amplify the signal (select all that apply)? Group of answer choices a) ligand binding to receptor b) release of GTP bound form of G protein from receptor c) binding of GTP bound form of G protein to target enzyme d) generation of second messenger by activated target enzyme e) activation of gene expression
Describe the heptahelical receptor endocytic pathway, including characteristics of ligand, recept...
Describe the heptahelical receptor endocytic pathway, including characteristics of ligand, receptor, and interactions with effector molecules involved in the receptor-mediated internalization for either recycling or lysosomal targeting and explain how these pathways affect GABA-mediated inhibition of neuronal excitability. Include an explanation on how GABA A and GABA B receptors differ.
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both...
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both the ligand and the substrate undergo a chemical change both the receptor and the enzyme alter their activities after the interaction they both rely on covalent binding D 6. Electron carriers like NADH and FADH2 are what type of molecules? enzymes receptors lipids proteins coenzymes
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both the ligand and the substrate undergo a chemical change both the receptor and the enzyme alter their activities after the interaction they both rely on covalent binding D 6. Electron carriers like NADH and FADH2 are what type of molecules? enzymes receptors lipids proteins coenzymes
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