can you reduce imines using NaBH4?
One molecule of NaBH4 can in theory reduce four ketone functional groups. If you had 25 mg of NaBH4, how many many mg of benzil could be fully reduced?
can NaBH4 reduce two ketones ? how many H’s does LiALH4 deliver?
Does NaBH4 reduce aldehydes, esters, or both?
1. Similarly to ketones, imines can be utilized as carbon nucleophiles. Draw the mechanism how imine G has been formed starting from ketone H and amine l H2N cat. H
1. Explain why one molecule of NaBH4 will reduce only two molecules of benzil. 2. In the case of reducing benzil, how many stereo centers will be produced?
19.59 Identify the reactants that you would use to make each of the following imines: (b) 19.60 Identify the reactants that you would use to make each of the following enamines: 19.61 Predict the major product(s) obtained when each of the follow- ing compounds undergoes hydrolysis in the presence of H30 19.62 Identity all of the expected products when below is treated with aqueous acid: roducts when the compound Excess H3O+
3. NaBH4 usually reacts slowly or not at all with esters. Therefore, LiAlH4 is often needed to reduce esters. Why do you think LiAlH4 is more reactive than NaBH4 (Hint: Compare the electronegativity of H versus Al or B).
Amines can act as 1 point O Nucleophiles Bronsted Bases Both as Nucleophile and Bronsted base O Neither as Nucleophile nor Bronsted base Clear selection Amides + LiALH4 = amines 1 point True False Imines + NaBH4 = amines 1 point true false amides + Br2 in NaOH = amines 1 point true
Please answer these 4 questions ( the last is true or false) 1/e/1FAIpQLSfd3_E6agftGrb9xvg5KdM-PrG9u Amines can act as Nucleophiles Bronsted Bases Both as Nucleophile and Bronsted E Neither as Nucleophile nor Bronste Amides + LiALH4 = amines * O True O False Imines + NaBH4 = amines true O false amides + Br2 in NaOH = amines true
What is the mechanism of reduction of (+)-D- Camphor using NaBH4 in methanol to borneol and isoborneol?