If a drug was administered to a stimulated pre-synaptic neuron that blocked the release of its inhibitory neurotransmitter, the neurotransmitter syntheses are blocked, the amount of neurotransmitters available for release becomes substantially lower, this results in a decrease in neurotransmitter activity. Some drugs can decrease the rate of synthesis of neurotransmitters by affecting the synthetic enzyme(s) for that neurotransmitter.
Drugs which targets the neurotransmitter of major systems affect the whole system. For example in case of Cocaine intake, it blocks the re-uptake of dopamine back into the presynaptic neuron, leaving the neurotransmitter molecules in the synaptic gap for a longer period of time.Thus neurotransmitter continues to bind to the receptors on the postsynaptic neuron resulting in a pleasurable emotional response. The addiction to cocaine leads to the downregulation of some post-synaptic receptors. As the effects of the drug ceases off, a person can become depressed due to decreased probability of the neurotransmitter binding to a receptor.
If a drug was administered to a stimulated pre-synaptic neuron that blocked the release of its...
Consider the neuromuscular junction between a pre-synaptic neuron and the diaphragm muscle. Acetylcholine is a neurotransmitter that is released from the presynaptic neuron to induce muscle contraction in the post-synaptic muscle cell. Which of the following would be an effect of tetrodotoxin? A. More acetylcholine in the synapse of the neuromuscular junction with the diaphragm B. Less acetylcholine in the synapse of the neuromuscular junction with the diaphragm
Csondier the steps at synaptic trasmission (communication from one neuron to another across the synapse. describe two different ways that drugs can act at various points in the process of synaptic transmission. For each drug, describe 10) at what point in the process of synaptic transmission it acts, and what its effect is, 2 what effect this has on the amount of neurotransmitter available in the synapse, and 3) what effect this has on the post-synaptic cell.
FILL IN THE BLANK. 1. Type of summation occurring when numerous different pre-synaptic neurons release neurotransmitter simultaneously onto a synapse 2. Occurs due to an increase in membrane permeability to K 3. Receptors that provide the CNS with information about body position 4. Term relating to a conscious recognition of the position of body parts with respect to one another as well as recognition of limb movement rates Large cells filled with myelin which surround the axons of somatic motor...
Consider the neuromuscular junction between a pre-synaptic neuron and the muscle around the eye. Which of the following would be an effect of the Botox? A. More acetylcholine in the synapse of the neuromuscular junction B. Less acetylcholine in the synapse of the neuromuscular junction
Which of the following would be an effect of consuming caffeine in your morning coffee? [Select all that apply] A. Adenosine cannot bind its receptor B. Adenosine cannot induce its inhibitory effects on the post-synaptic neuron C. Excitatory effects on the post-synaptic neuron, due to the lack of inhibitory effect of adenosine on the post-synaptic neuron D. More action potentials on the post-synaptic neuron, leading to increased alertness
2. Long-term Potentiation is a process that strengthens the transmission of a single synapse in a circuit. This is achieved when pre-synaptic cells and post-synaptic cells fire action potentials at the same time. Usually multiple pre-synaptic cells synapse onto one post-synaptic cell, increasing the probability of inducing an action potential in the post- synaptic cell. You may need to refer to your textbooks or online resources for this question, as we do not cover this in explicit detail in class....
Based on your excellent understanding and extensive knowledge of chemical synaptic transmission, EXPLAIN what would happen in response in each hypothetical situation below….Assume you have an experimental set-up with two neurons connected via a chemical synapse – Neuron A is presynaptic and Neuron B is postsynaptic. Also assume that there is a stimulating electrode in Neuron A that brings it to threshold and produces an EPSP in Neuron B. In your answers, include all relevant events between this stimulus and...
8 A reflex are a) is the simplest neural circuit b) requires a receptor, sensory neuron, integration center, motor neuron e) san cause a motor response before a person is consciously aware of it All the above (a, b and c) are corect 9. The correct distribution of spinal nerves is I coccygeal a) 4 cervical, 16 thoracie, 3 lumbar, 8 sacral and b) 12 cervical, 12 thoracic, 3 lumbar, 8 sacral and I coccyseal c) 8 cervical, 12 thoracic,...
How do neurons conduct information? (Please note: this question refers only to events occurring during the time from the receipt of an external signal by a single neuron to the time this information is relayed to the next neuron or muscle. It does not include anything relating to the initial sensory neuron that stimulated the neuron in question, or the subsequent neuron or muscle that this neuron stimulates.) a. What kind of protein “senses” incoming information at the post-synaptic membrane?...
1. The following statement is similar to those you might see on exams. Write a paragraph of 3-5 sentences describing 1) whether the statement is correct or incorrect and 2) the reasoning for your answer. Your answer should demonstrate your understanding of the physiological concepts underlying the statement and be written professionally. At a chemical synapse, the release of neurotransmitter occurs in response to a graded depolarization of the synaptic terminal. 2. Write a paragraph of 3-5 sentences answering the...