Consider the neuromuscular junction between a pre-synaptic neuron and the diaphragm muscle. Acetylcholine is a neurotransmitter...
Consider the neuromuscular junction between a pre-synaptic neuron and the diaphragm muscle. Acetylcholine is a neurotransmitter that is released from the presynaptic neuron to induce muscle contraction in the post-synaptic muscle cell. Which of the following would be an effect of tetrodotoxin?
A. More acetylcholine in the synapse of the neuromuscular junction with the diaphragm
B. Less acetylcholine in the synapse of the neuromuscular junction with the diaphragm
Homework Answers
SOLUTION
Tetrodotoxin is the neurotoxin responsible for blocking sodium channel present on axon terminal.
sodium ion channel are responcible for increase in action potential and transfer it upto terminal of axon for calcium intake for acytylcholin release.
as tetrodoxin block this sodium ion so calcium ion transporter also closed.if calcium ions are not taken inside then no acetylcholin is released into synaptic cleft.
so correct answer is B.
THAT THERE WILL BE LESS ACYTYLCHOLIN IN SYNAPSES OF THE NEUROMUSCULAR JUNC५ION.
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