Explain the pathway the drug Taxol interferes with. How is this pathway different in normal versus cancer cells?
Taxol drug used to inhibit the tubulin. It usually stabilize the microtubules polymer and does not allow to dissociate during mitosis.
So this causes late division which result in apoptosis or enters into G0 stage of cell.
In normal cell division is under control the checkpoints and it occurs only when required.
While in case of cancer cell they divide enormously and leads to tumor formation. So this taxol inhibit the tubule and stop cell division.
Explain the pathway the drug Taxol interferes with. How is this pathway different in normal versus...
Look up the following cancer drugs/therapyand explain how each works. In your answer include mechanism of action, drug/therapytarget (specific protein), and specific pathway targeted. Explain why this is an anti-cancer drug/therapy(what is it doing to the cancer cells?) Be sure to include references used .a.ABT-737 b.ONYX-015 c.vinblastine d.cyclapolin e.TNP-470
Taxol is a cancer chemotherapy drug isolated from the bark of the pacific yew tree, and name five (4) major functional groups. Bonus) 1-Dccanol is an important reagent used in the synthesis of surfactants, lubricants and plasticizers. On a lab scale 1-decanol can be produced from 1 decene via a hydroboration-oxidation reaction. Assume that each mole of alkene is converted into 1 mole of alcohol. How much alkene starting material will you to produce 1 Kg of alcohol Molar mass...
Normal human blood plasma, glucose concentration is ~5mM. Explain (state pathway(s) and key enzyme(s) in processing glucose in muscle cells) the fate(s) of glucose once it is delivered by blood plasma to myocytes (muscle cells).
Explain how graphs of weight versus normal force in procedures A and B give the coefficients of friction.
For the drug NEXIUM describe briefly the normal cell biology, the pathogenic state and how the drug alters the pathogenic state. Remember - “a picture is worth a thousand words” – the use of a figure depicting a pathway map and indicating the point at which the drug acts is highly encouraged. Furthermore, you will develop and present an experimental plan by which you can prove where in the cell the drug acts; what cellular functions it modulates and the mechanism...
1. Define normal versus disordered eating patterns 2. Explain how you think a normal eating pattern could morph into a disordered eating pattern and how this could contribute to being overweight or obese. F 3. What is Orthorexia Nervosa? Do you think this condition may play a role in obesity? If yes, explain how.
explain what is the difference between glycolysis in cancer cells ( The Warburg Effect) vs normal cells and how do you think this will impact the cells overall metabolism?
(5 pts) Discuss how the ECL cells of the gastric mucosa function as a final common pathway for the neural, endocrine and paracrine regulation of gastric acid secretion. What does this imply about the effectiveness of drug intervention to block excessive acid secretion? (5 pts) Discuss how the ECL cells of the gastric mucosa function as a final common pathway for the neural, endocrine and paracrine regulation of gastric acid secretion. What does this imply about the effectiveness of drug...
You are trying to design a drug that can be used to treat cancer and you decide that your drug will target the cell cycle. Explain how your drug would work (1 sentence) and why this would be useful in treating cancerous cells (1 sentence)
please explain these three things : 1.) a protooncogene and it’s function and how it differs from a normal version of the gene when it’s cancerous 2.) why so many cancer cells duplicate uncontrollably vs normal cells and why normal cells only divide 20 times 3.) how dna turns into pre rna and then mrna , and draw an example