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Explain the pathway the drug Taxol interferes with. How is this pathway different in normal versus...

Explain the pathway the drug Taxol interferes with. How is this pathway different in normal versus cancer cells?

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Answer #1

Taxol drug used to inhibit the tubulin. It usually stabilize the microtubules polymer and does not allow to dissociate during mitosis.

So this causes late division which result in apoptosis or enters into G0 stage of cell.

In normal cell division is under control the checkpoints and it occurs only when required.

While in case of cancer cell they divide enormously and leads to tumor formation. So this taxol inhibit the tubule and stop cell division.

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