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A 35-year old male with headache, fatigue, light-headedness, dyspnea (difficulty in breathing), and tachycardia (rapid heart...

A 35-year old male with headache, fatigue, light-headedness, dyspnea (difficulty in breathing), and tachycardia (rapid heart rate). Laboratory findings reveal anemia, presence of red blood cell spherocytes, and a positive direct Coomb's test (presence of auto-antibodies on red blood cell surfaces). The patient is currently taking an antibiotic for symptoms of upper respiratory infection. These findings suggest that the antibiotics may have triggered an autoimmune disease which can also be classified as which type of hypersensitivity disease?

a. Type II mediated by IgG antibodies

b. Type III mediated by IgA antibodies

c. Type IV mediated by CD4 T cells

d. Type I mediated by IgE antibodies

e. Type III mediated by IgM antibodies

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Answer #1

The answer will be type II mediated by IgG antibodies (Option a).

Explanation: Type II hypersensitivity reaction is mediated by IgG or IgM antibodies & is responsible triggering an autoimmune disorder. Among the given options only option a contains correct answer. Thus, correct answer will be option a.

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