Why does a succinate dehydrogenase deficiency produce the same symptoms as a fumarase deficiency?
Why does a succinate dehydrogenase deficiency produce the same symptoms as a fumarase deficiency?
In a metabolic pathway, succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by malonic acid, a substance that resembles succinate but cannot be acted upon by succinate dehydrogenase. Increasing the amount of succinate molecules to those of malonic acid reduces the inhibitory effect of malonic acid. What role does malonic acid play with respect to succinate dehydrogenase? In a metabolic pathway, succinate dehydrogenase catalyzes the conversion of succinate to fumarate. The reaction is inhibited by...
Succinate Dehydrogenase is an enzyme used to produce an intermediate product, fumerate, during the Krebs Cycle. The gene (DNA) that encodes succinate dehydrogenase is found on a chromosome in the nucleus. Fully describe the production, targeting/delivery and activity of succinate dehydrogenase by a cell. Give as many molecular details as you can. Be sure to include: 1. Where the gene is transcribed. 2. how the mRNA moves to the area where it will be translated, 3. how and where where...
Select the single best answer. To what class of enzymes does succinate dehydrogenase belong? Explain your answer. Succinate dehydrogenase is an oxodoreductase, because it catalyzes the oxidation of succinate to fumarate. Succinate dehydrogenase is a transferase, because it catalyzes, the oxidation of isoitrate to a ketoglutarate. Succinate dehydrogenase is a transferase, because if catalyzes the transfer of a phosphoryl group from GTP to ADP to make ATP. Succinate dehydrogenase is a hydrolase, because it catalyzes the addition of H_2 O...
2. Based on your experimental observations, what can you conclude concerning the distribution of succinate dehydrogenase? Is the distribution what you would have expected? Explain why or why not.
1. Why would the homogenate fraction have the highest succinate dehydrogenase activity and thus the most mitochondria ( more than the S1,P1,S2 and P2 fraction). SDH activity Initial Velocity (Abs./s) P1 Fractions Figure 2. The SDH of each fraction measured in velocity (Abs./sec). The H fraction had the highest initial velocity of 0.057 Abs./s while the P2 fraction had the lowest initial velocity of 0.0033 Abs./s.
If zinc deficiency occurs, the symptoms will present in what way? Select all that apply. A. stunted growth B. impaired collagen synthesis C. slow wound healing D. anemia E. weakness in bone and joint formation F. muscle spasms G. nonfunctioning carboxypeptidase and alcohol dehydrogenase
Why Pythagoras wouldn’t eat Falafel: A story about Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency Fava beans, an ingredient of falafel, have been an important food source in the Mediterranean and Middle East since antiquity. The Greek philosopher and mathematician Pythagoras prohibited his followers from dining on fava beans, perhaps because they made many people sick with a, sometimes fatal, condition called favism. In favism, erythrocytes begin to lyse 24-48hrs after ingestion of the beans, releasing free haemoglobin into the blood. Jaundice and...
Why does succinate DH give electrons to FADH2 rather than NADH? This requires looking at the electrochemical reduction potentials.
, why does a deficiency of estrogen in women lead to osteoporotic change?
Pyruvate dehydrogenase and glyceraldehyde 3 phosphate dehydrogenase use NAD as an electron acceptor, why don't the two enzymes compete for the same pool of cellular NAD?