Pyruvate dehydrogenase and glyceraldehyde 3 phosphate dehydrogenase use NAD as an electron acceptor, why don't the...
Pyruvate dehydrogenase and glyceraldehyde 3 phosphate dehydrogenase use NAD as an electron acceptor, why don't the two enzymes compete for the same pool of cellular NAD?
Homework Answers
Pyruvate dehydrogenase is situated in the mitochondrion.
Glyceraldehyde 3-phosphate dehydrogenase in the cytosol.
Since the mitochondrial and cytosolic pools of NAD are isolated by the internal mitochondrial layer. the chemicals don't vie for a similar NAD pool.
In any case, lessening reciprocals are moved from one nicotinamide coenzyme pool to the next through transport systems.
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Pyruvate dehydrogenase and glyceraldehyde 3 phosphate
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The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In step 1 (Top Left) the sulfur from the cysteine loses its...
The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In
step 1 (Top Left) the sulfur from the cysteine loses its hydrogen
to the carbonyl carbon of the substrate. I think is wrong and the
hydrogen is stolen by the histidine (nitrogen) using a base
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2.
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Question 3 (4 points) The enzyme glyceraldehyde 3-phosphate dehydrogenase catalyzes the reaction glyceraldehyde 3- phosphate → 1,3 diphosphoglycerate. The region of the enzyme where glyceraldehyde 3-phosphate binds is called the transition state. O groove. catalyst. active site.
The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In
step 1 (Top Left) the sulfur from the cysteine loses its hydrogen
to the carbonyl carbon of the substrate. I think is wrong and the
hydrogen is stolen by the histidine (nitrogen) using a base
catalyst reaction.
lser Glyceraldehyde 3-phosphate NAD CONH2 H -N + HH Hemithioacetal Oxidation NAD NADH CONH CONH2 Но RN + H -N / H Η Η Hн s NADH NAD Thioester intermediate Thioester intermediate Phosphorylation CONH2 O...
1.
2.
3.
4.
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