Homework Answers
Glyceraldehyde-3-phosphate binds on active site of the enzyme.
4th option is right Answer
Add Answer to:
Question 3 (4 points) The enzyme glyceraldehyde 3-phosphate dehydrogenase catalyzes the reaction glyceraldehyde 3- phosphate →...
The conversion of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate is catalyzed by the enzyme glyceraldehyde 3-phosphate dehydrogenase. Formation...
The conversion of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate is catalyzed by the enzyme glyceraldehyde 3-phosphate dehydrogenase. Formation of the enzyme-substrate complex involves nucleophilic attack by an active site cysteine residue on glyceraldehyde 3-phosphate to form a tetrahedral intermediate. However, cysteine-dependent nucleophilic attack only occurs when NAD+ is bound, which depresses the pKR for cysteine from 8 to 5.5. Please propose an alternative active site arrangement that may lead to the formation of a tetrahedral covalent intermediate without the requirement for NAD+...
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the phosphorylation of glyceraldehyde-3-phosphate, but unlike other glycolytic reactions, it does not require...
Glyceraldehyde-3-phosphate dehydrogenase catalyzes the phosphorylation of glyceraldehyde-3-phosphate, but unlike other glycolytic reactions, it does not require energy investment from ATP. This reaction occurs in two stages: oxidation/reduction and phosphorylation. Why is the oxidation/reduction reaction necessary to make phosphorylation favorable? Choose one: A. The oxidation/reduction reaction is necessary to oxidize phosphate, allowing addition to the substrate. B. The oxidation/reduction reaction is necessary to form an intermediate with a large free energy of hydrolysis. C. The oxidation/reduction reaction is necessary to produce...
The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In step 1 (Top Left) the sulfur from the cysteine loses its...
The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In
step 1 (Top Left) the sulfur from the cysteine loses its hydrogen
to the carbonyl carbon of the substrate. I think is wrong and the
hydrogen is stolen by the histidine (nitrogen) using a base
catalyst reaction.
lser Glyceraldehyde 3-phosphate NAD CONH2 H -N + HH Hemithioacetal Oxidation NAD NADH CONH CONH2 Но RN + H -N / H Η Η Hн s NADH NAD Thioester intermediate Thioester intermediate Phosphorylation CONH2 O...
35) The overall reaction of glyceraldehyde 3-phosphate dehydrogenase (GAP glyceraldehyde 3-phosphate + NAD+ + P =...
35) The overall reaction of glyceraldehyde 3-phosphate dehydrogenase (GAP glyceraldehyde 3-phosphate + NAD+ + P = 1,3-bisphosphoglycerate + NADH GAPDH couples together two reactions with favorable (AG'°-50 kj/mol) and unfavorable (AG' +50 kJ/mol) Gibbs free energies, respectively. a) (6 pts) Write the balanced chemical equations for the two separate reactions. b) (6 pts) Draw the structure of the thiohemiacetal intermediate and show the mechanism for generating the acyl thioester intermediate. 36) (4 pts) Under anaerobic conditions, lactic acid fermentation regenerates...
Match the enzyme to the substrate --> product reaction to which it catalyzes. O Hold and...
Match the enzyme to the substrate --> product reaction to which it catalyzes. O Hold and drag to reorder Phosphoglycerate Mutase Glucose --> Glucose 6-phosphate Phosphohexose Isomerase 1-3- Bisphosphoglycerat e--> 3- Phosphoglycerate Hexokinase Fuctose 1-6- bisphophate --> Glyceraldehyde 3- phosphate + Dihydroxyacetone phosphate Phosphoglycerate Kinase Oxaloacetate --> Phosphoenolpyruva te Aldolase Mannose 6- phosphate -> Fructose 6- phosphate Pyruvate kinase Dihydroxyacetone phosphate -> Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosp Bisph Submit Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosphate -> 1-3-...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
is meant by a "pacemaker" enzyme is an enume that catalyzes the fastest reaction in a...
is meant by a "pacemaker" enzyme is an enume that catalyzes the fastest reaction in a pathway A It is an nuryme the catalyzes the slowest reaction in a pathway c) It is in en ryme that requires a significant energy source to function D) It is an enzyme that requires a co-factor to function E) It is an enzyme that is covalently modified during the reaction process 24. What is the difference bet between the lock-and-key and the induced-fit...
14. Which step of reaction requires inorganic phosphate? What is the enzyme? Which enzyme category does...
14. Which step of reaction requires inorganic phosphate? What is the enzyme? Which enzyme category does it belong to? 15. Which step of reaction produces H20 as a byproduct? P-0-CH CH - Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate triose phosphate -O-CH2 -CHCH isomerase 2NAD Ilyceraldehyde oxidation and (b) Payoff phase Oxidative conversion of (2) Glyceraldehyde (21 -0-CH -CH glyceraldehyde 3-phosphate 3-phosphate to pyruvate and the coupled 2P IN 6 formation of ATP and NADH 2NAD I 3 phosphate Jl dehydrogenase phosphorylation 2...
Identify the type of high energy bond in the intermediate of the glyceraldehyde-3-phosphate dehydrogenase reaction. What...
Identify the type of high energy bond in the intermediate of the glyceraldehyde-3-phosphate dehydrogenase reaction. What is the importance of this bond for the energetics of the reaction? L a nthus are regulated? How are they regualted
1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate...
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
The mechanism of glyceraldehyde 3 phosphate dehydrogenase. In
step 1 (Top Left) the sulfur from the cysteine loses its hydrogen
to the carbonyl carbon of the substrate. I think is wrong and the
hydrogen is stolen by the histidine (nitrogen) using a base
catalyst reaction.
lser Glyceraldehyde 3-phosphate NAD CONH2 H -N + HH Hemithioacetal Oxidation NAD NADH CONH CONH2 Но RN + H -N / H Η Η Hн s NADH NAD Thioester intermediate Thioester intermediate Phosphorylation CONH2 O...
35) The overall reaction of glyceraldehyde 3-phosphate dehydrogenase (GAP glyceraldehyde 3-phosphate + NAD+ + P = 1,3-bisphosphoglycerate + NADH GAPDH couples together two reactions with favorable (AG'°-50 kj/mol) and unfavorable (AG' +50 kJ/mol) Gibbs free energies, respectively. a) (6 pts) Write the balanced chemical equations for the two separate reactions. b) (6 pts) Draw the structure of the thiohemiacetal intermediate and show the mechanism for generating the acyl thioester intermediate. 36) (4 pts) Under anaerobic conditions, lactic acid fermentation regenerates...
Match the enzyme to the substrate --> product reaction to which it catalyzes. O Hold and drag to reorder Phosphoglycerate Mutase Glucose --> Glucose 6-phosphate Phosphohexose Isomerase 1-3- Bisphosphoglycerat e--> 3- Phosphoglycerate Hexokinase Fuctose 1-6- bisphophate --> Glyceraldehyde 3- phosphate + Dihydroxyacetone phosphate Phosphoglycerate Kinase Oxaloacetate --> Phosphoenolpyruva te Aldolase Mannose 6- phosphate -> Fructose 6- phosphate Pyruvate kinase Dihydroxyacetone phosphate -> Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosp Bisph Submit Glyceraldehyde 3- phosphate Enolase Glyceraldehyde 3- phosphate -> 1-3-...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
is meant by a "pacemaker" enzyme is an enume that catalyzes the fastest reaction in a pathway A It is an nuryme the catalyzes the slowest reaction in a pathway c) It is in en ryme that requires a significant energy source to function D) It is an enzyme that requires a co-factor to function E) It is an enzyme that is covalently modified during the reaction process 24. What is the difference bet between the lock-and-key and the induced-fit...
14. Which step of reaction requires inorganic phosphate? What is the enzyme? Which enzyme category does it belong to? 15. Which step of reaction produces H20 as a byproduct? P-0-CH CH - Glyceraldehyde 3-phosphate Dihydroxyacetone phosphate triose phosphate -O-CH2 -CHCH isomerase 2NAD Ilyceraldehyde oxidation and (b) Payoff phase Oxidative conversion of (2) Glyceraldehyde (21 -0-CH -CH glyceraldehyde 3-phosphate 3-phosphate to pyruvate and the coupled 2P IN 6 formation of ATP and NADH 2NAD I 3 phosphate Jl dehydrogenase phosphorylation 2...
Identify the type of high energy bond in the intermediate of the glyceraldehyde-3-phosphate dehydrogenase reaction. What is the importance of this bond for the energetics of the reaction? L a nthus are regulated? How are they regualted
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
Most questions answered within 3 hours.
-
Oxidative phosphorylation is achieved through chemiosmotic
coupling, which turns chemical energy into osmotic potential energy
that...
asked 2 hours ago -
Hollywood Shoes would like to maintain their cash account at a
minimum level of $64,000, but...
asked 2 hours ago -
Proteins CtrA-P, DnaA, and GcrA behave similarly to what
molecule in the Eukaryotic Cell Cycle?
asked 2 hours ago -
TRUE OR FALSE
In case of a competitive tender procedure, in the request for
quotation, the...
asked 2 hours ago -
I am a little behind please provide some explanation, will
provide thumbs up.
This question considers...
asked 2 hours ago -
Let say the utility function as U(X,Y) = lnX + Y. Show that the
marginal rate...
asked 2 hours ago -
A current of I=8.0A is flowing in a typical extension cord of
length L=3.00m. The cord...
asked 2 hours ago -
1. When balancing the equation H2SO4 (aq) + NaOH (aq) →
Na2SO4(aq) + H2O(aq), would you...
asked 3 hours ago -
Provide a definition of “classification hierarchy” and
illustrate your definition with an example of how and...
asked 3 hours ago -
1. Describe the four main green solvents. Provide one example of
the use of each solvent....
asked 3 hours ago -
International ethics focus on:
1) exploitation of labor
2)corruption
3) environmental impact
4) none of the...
asked 3 hours ago -
Costing Models You work for XYZ trucking and your boss has asked
you to figure out...
asked 3 hours ago