The carboxylic acid group (COOH) in the side chain of Aspartic acid (shown below), one of the 20 naturally occurring amino acids, has a pKa of 4.1. Calculate the percentage of conjugate base (COO- ) for this carboxylic acid group in the side chain of Aspartate at the following pH values: 2.1 , 4.1 and 5.1.
The carboxylic acid group (COOH) in the side chain of Aspartic acid (shown below), one of...
help with this question Consider a 0.211 L solution of the amino acid aspartic acid (0.631 M), which has an alpha carboxylic acid group (pka = 2.10), an alpha amine group (pka = 9.82), and a carboxylic acid group in the side chain (pka = 3.86). If the titration is started at a very low pH, how many liters of 2.25 M NaOH would you need to add to reach the isoelectric point of the amino acid? Give your answer...
Consider a protein with the acidic side chains, Amino Acid side-chain Arginine pKa = 12.48 Aspartic Acid PKa = 3.90 Cysteine pKa = 8.33 Glutamic acid pKa = 4.07 Histidine pKa = 6.04 Lysine pKa =10.79 Tyrosine pKa =10.13 Given that the pH of blood is about 7.3, how many of the above side chains would be mostly in their ionic form (A-) in blood? 2 3 4 5
Consider a 0.203 L solution of the amino acid aspartic acid (0.615 M), which has an alpha carboxylic acid group (pka = 2.10), an alpha amine group (pka = 9.82), and a carboxylic acid group in the side chain (pka = 3.86). If the titration is started at a very low pH, how many liters of 2.15 M NaOH would you need to add to reach the isoelectric point of the amino acid? Give your answer to 3 significant figures...
1. An amino acid is shown below. Draw a circle around the carboxylic acid group, a square around the side chain and a triangle around the amino group. Finally, put an asterisk next to the C-carbon. HC=0 -C-C-H HNH3+ 2. Consider the molecule below (C&H BINO). After downloading Imol and the molecule files to your computer, measure the values of the indicated bond and torsional angles. CCN HOC = HO 1 OCCC - OCCBr =
Question 2 1 pts Amino acids are classified by their Rgroup (side chain) carboxylic acid group peptide bond alpha carbon amine group
1A solution of 0.235 M aspartic acid, the charge neutral form of the amino acid, is titrated with 0.118 M NaOH . The p K a values for aspartic acid are 1.990 , 3.900 , and 10.002 , corresponding to the α-carboxylic acid group, the β-carboxylic acid group, and the amino group, respectively. Calculate the pH at the first equivalence point of this titration.
The one-letter sequence is: WATER a) Draw the peptide (R-groups trans), indicating charges, in predominant form found at pH = 0. b) What is the isoelectric point? c) What is the average charge on the population of peptide macromolecules at pH = 2.2? d) What is the average charge on the population of peptide macromolecules at pH = 12.5? TABLE 4.1 Amino Acid Alanine Arginine Asparagine Aspartic acid Cysteine....« Glutamic acid Glutamine Glycine Histidine Isoleucine Leucine Lysine … Methionine Phenylalanine...
I dont really know how to do this question A8 Two acid dissociation constants (pka) of the amino acid aspartic acid are shown below. The measured isoelectric point (pl) is 3.0. What is the pka of the carboxylic acid side chain? PK, 9.8 pk, 2.1 *H3N он Questions continue over page
A8 The acid dissociation constants (pKa) of the amino acid aspartic acid are shown below. What is the isoelectric point (pl) of this amino acid? pk, 9.8 ΤΗΝ PK, 2.1 TOH OS pk 3.9 ОН (A) 6.9 (B) 6.0 (C) 3.9 (D) 3.0 (E) 2.1
A non-natural amino acid has been synthesized. The carboxylic acid has a pk - 3.21, the protonated amine has a pk = 9.59, and the side chain contains an alcohol which has a pk = 16.09. What is the pl of this amino acid? Your answer should be to the nearest hundredths. a Answer: For each compound, indicate if it will or will not produce one of the 20 naturally occuring amino acids if used as the starting material in...