What is the specific mechanism of action for temozolomide? (doesn't have to be very in depth, just an overview)
Temozolomide is the drug used in the treatment of brain cancer, etc. It's mechanism of action is based on ability of its metabolites to deposit methyl groups on guanine bases of DNA.
Temozolomide gets converted into MTIC i.e. 3-methyl-(triazen-1-yl) imidazole-4-carboxamide which methylates DNA as a result cellular repair mechanism cannot adjust due to which DNA break down into small pieces resulting death of cells.
What is the specific mechanism of action for temozolomide? (doesn't have to be very in depth,...
An affirmative action program , by its very nature, focuses on race, doesn't it? If not for affirmative action, what else can be done to help promote diversity? Do we still need affirmative action programs in place today when we have so many anti discrimination laws in place? Anyone?
protease action of Chymotrypsin as a model of a specific type of enzyme mechanism. Answer the following questions about chymotrypsin. List the residues involved in the “catalytic triad”: What is the specificity of Chymotrypsin? (where does it cut) What type of protease is Chymotrypsin? What type of general enzyme mechanism is used by chymotrypsin? What is the oxyanion hole used for? Briefly outline the steps in catalysis for the enzyme.
what is the difference between site of action and mechanism of action ?
1. A 1 kg fish lives at a depth of 300 m in seawater. The specific density of the fish, excluding its swim bladder, is 1.07 A To be neutrally buoyant at this depth, what fraction of the fish's volume must its swim bladder fill? B What is the gas pressure inside the swim bladder at this depth? C Suppose that the fish suddenly descends to 400 m. The gas in its swim bladder will contract under pressure, and the...
What is the mechanism of action for monoclonal antibodies? Target tumor-specific antigens on the surface of some cancer cells Introduce the immune system to fragments of weakened or dead bacteria Accelerate and fully engage immune cells to create a robust immune response Remove immune cells from the body, and retrain them to identify and kill specific antigens Question 24 A patient scheduled to receive a fourth cycle of cetuximab states that she experienced nausea and vomiting with her previous cycles despite an optimal antiemetic regimen. Which...
True or False? Antibiotics have the same mechanism of antimicrobial action as bleach
Enzymes have very specific shapes to perform their function. What part of an enzyme interacts with a substrate so the enzyme can catalyze a reaction?
Hi! I need a complete information for a project. I need the mechanism of action of the TCA of Amitryptiline (Antidepressant), i need the pharmacodymamic (what the drug does in the body?), in terms of Biochemistry. Please explain me: (use drawings): 1. Use bilogical terms to explain what is happening with this medicament in the neurons. Explain the mechanism of action with molecules. What is happening with serotonin, where did it come from). What happen with the cardiogrma of an...
what is zantac used to treat and what is its mechanism of action? 54. What is Zantac used to treat and what is its mechanism of activity? Zantac is ed to trat acid reF this by stimuldy te ells to seorte lous gra Cenentkn uf and.
QUESTION 35 and their mechanism of action is to Thyroid hormones have receptors A. inside the cell; activate transcription B. in the cell membrane; activate protein synthesis C. inside the cell; activate translation D. in the cell membrane: activate a protein