Describe the effects of insulin resistance on the lipoprotein metabolism.
According to Howard BV,
The dyslipidemia also described as abnormal amount of fat or lipids present in the blood which is caused by the insulin resistance contains mainly triglyceride levels, decreased high-density lipoprotein (HDL) cholesterol, and changes in the composition of low-density lipoprotein (LDL) cholesterol in the blood. Hyperinsulinemia which is the another condition where the quantity of insulin present in blood is very high than the glucose and obesity which is by the insulin resistance which lead to overproduction of very low-density lipoprotein (VLDL) cholesterol, and this also results like the conditions of dyslipidemia, so from these obsevations one can say that the insulin resistance which increses the production of low density lipids and triglyceride levels in the blood.
Describe the effects of insulin resistance on the lipoprotein metabolism.
16. Briefly describe the action of Insulin on carbohydrate metabolism, fat metabolism, and on protein metabolism. I.e. do es it promote (+) or discourage (-) the following? a. Glycogenesis (production of glycogen) b. Glycogenolysis (breakdown of glycogen) c. Glycolysis: using glucose for fuel inside cells d. Gluconeogenesis: Production of glucose by liver (usually from aa) e. Uptake of glucose into fat and muscle cells? f. Lipid synthesis: Production of Triglycerides in fat cells g. Lipid breakdown/mobilization of fat from adipocytes(breakdown...
14. Insulin resistance influence insulin production over time. In the early phases if insulin resistance, are blood levels of insulin higher or lower than "normal"? 15. Describe a. How does metformin control blood sugar? b. How does Metformin impact risk of hypoglycemia c. How doe Metformin impact risk of weight gain?
Serotonin is a downstream product of Amino Acid metabolism. Describe this process and the possible effects that dietary proteins can have on mood and higher-order brain function.
The adipose tissue is an important regulator of energy metabolism. In obese patients with insulin resistance, fatty liver develops in only a subset of the population. What is the result of adiiponectin administration to mice while feeding alcohol in Figure 2? Figure 2 Effects of adiponectin on alcohol-induced steatosis and inflammation. Liver specimens were taken from mouse livers after 5 weeks of LC diet (a and d), LE diet (b and e), or LE + Ad diet (c and f)...
Are the effects of insulin related to the amount of insulin secreted?
How do the hormones (insulin, glucagon, epinephrine, and cortisone) regulate metabolism? What are the roles of enzymes or vitamins?
how do the hormones (insulin,glucagon,epnephrine and cortisone) regulate metabolism? what are the roles of enzymes or vitamines
What is the relationship between insulin resistance and hyperinsulinemia?
Based on your knowledge of cell signaling and interorgan metabolism, describe how the fuel metabolism of the liver, adipose tissue, skeletal muscle, heart and brain are affected in type I diabetics (assuming no insulin shot has been used) immediately after a meal and between meals. Include what pathways have been affected (glycolysis, glycogen synthesis, etc) and what the organ/tissue uses as a fuel source.
6. Explain how VLDL is metabolized by lipases to intermediate-density lipoprotein (IDL) which may be cleared by the liver or converted to lowdensity lipoprotein (LDL), which functions to deliver cholesterol from the liver to extrahepatic tissues via the LDL (apoB100, E) receptor. 7. Explain how high-density lipoprotein (HDL) is synthesized, indicate the mechanisms by which it accepts cholesterol from extrahepatic tissues and returns it to the liver in reverse cholesterol transport. 8. Describe how the liver plays a central role...