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A number of mutants were isolated in yeast that are auxotrophic for leucine. Different crosses were...

A number of mutants were isolated in yeast that are auxotrophic for leucine. Different crosses were performed between the different Leu- strains. In which of the following crosses would a geneticist expect the resulting diploid to grow on medium lacking leucine?

A. A diploid containing two mutant alleles of the same gene that have the same nucleotide sequence.

B. A diploid containing two mutant alleles of the same gene that have different nucleotide sequences.

C. A diploid with a point mutation in one gene and a deletion in a different gene.
D. A diploid with a point mutation in one gene and a deletion mutation in the same gene.

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Answer #1

C). A diploid with a point mutation in one gene and a deletion in a different gene.

Different mutants will have different mutations at different gene that participates in different genes involved in leucine utilisation oathway and upon crossing if both have mutation at different gene, due to complementary effect it will result in diploid that can grow in leucine

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