Which factor is not a DNA‑binding domain found in regulatory proteins?
A. RNA recognition motif
B. DNA recognition motif
C. helix‑turn‑helix
D. homeodomain
Which factor is not a DNA‑binding domain found in regulatory proteins? A. RNA recognition motif B....
DNA‑binding domains recognize and bind to specific DNA sequences. Complete the sentences. The homeodomain is also called the homeobox domain. Not all words will be used. Two terms will be used more than once. A 1.) contains a metal ion in coordination with two cysteine and two histidine residues or with four cysteine residues. DNA–protein binding generally occurs in the 2.) of DNA. The 3.) , found in eukaryotes, contains a small DNA‑binding region similar to the helix‑turn‑helix motif....
Select the correct statement about DNA binding proteins. For proteins that have a helix-turn-helix motif, one of the alpha helices fits directly into the minor groove of DNA There are two classes of zinc finger motifs found in DNA binding proteins. One is characterized by pairs of cysteines and histidines (the C2H2-type). The second is the Cx-type. The function of both classes is to coordinate zinc. The leucine zipper motif has leucines at alternating residues of an alpha-helix. The hydrophobic...
Part A: How do proteins differentiate between ssRNA, dsRNA, DNA-RNA hybrids, and dsDNA? Part B: Why are the alpha helix and the beta sheet the most common secondary structure elements? Part C: Describe the two ways proteins can interact with DNA, and the differences between both. Which is similar to the RNA recognition motif?
Which of the following is NOT a DNA binding protein? Choose one: O A. histone proteins O B. ribosomal proteins O C. transcription factors O D. RNA polymerase
For the enhanceosome, binding sequences are on both strands of DNA. Why? The proteins of the enhanceosome on one strand have a regulatory function, whereas those on the other strand bend the DNA strand. The proteins on one side of the strand bind to GC rich regions and those on the other strand bind to AT rich regions. The proteins of the enhanceosome completely enclose the double helix and straightened the double helix. The proteins on one strand clear the...
(2) In isolation, a DNA-binding protein binds to its regulatory sequence with a Kd of 1.0 M. Another DNA binding protein binds to another sequence on the same DNA a few bases away with a Kd of 5.0 HM when alone. The two proteins each have a domain which binds to the other with an interaction energy of -2.7 kcal/mole: (a) Draw the thermodynamic box which represents all four states of this system (b) what are the affinities for each...
Which of the following statements is INCORRECT about enhancers. O A. The location and orientation of the enhancer is non-specific (they are functional regardless of their general location around an within a gene). B. Both activator and repressor proteins can bind to an enhancer. C.Enhancers can only exert their effect in one direction along the DNA. D. Enahncers can bind proteins to affect the architecture (structure) of the DNA. Reset Selection Question 5 of 5 Select all of the following...
The operator of thr operon is the binding site for? RNA polymerase DNA plymerase reprocessor proteins DNA isomerase
The recognition of specific DNA sequences by proteins is thought to depend on two types of mechanisms: one that involves the formation of hydrogen bonds with specific bases, primarily in the major groove, and one involving sequence-dependent deformations of the DNA helix. By comprehensively analyzing the three-dimensional structures of protein-DNA complexes, we show that the binding of arginines to narrow minor grooves is a widely used mode for protein-DNA recognition. This readout mechanism exploits the phenomenon that narrow minor grooves...
Nucleosome positioning along the DNA can influence where transcriptional regulatory proteins are able to bind DNA. If a nucleosome is bound to an enhancer sequence, it may outcompete a regulatory protein from binding the same sequence. Conversely, if an enhancer sequence is in the linker DNA where the nucleosome is absent, the regulatory protein does not have to compete with the nucleosome. The position of the nucleosome can alter the accessibility of a sequence of DNA to DNA binding proteins....