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How is the mechanism by which eukaryotic repressors function different from that by which prokaryotic repressors...

How is the mechanism by which eukaryotic repressors function different from that by which prokaryotic repressors function?

1. Bacterial repressors bind to operators and RNA polymerase simultaneously, inhibiting polymerase activity.

2. Eukaryotic repressors bind to silencers and RNA polymerase simultaneously, inhibiting polymerase activity.

3. Bacterial repressors directly block RNA polymerase from binding to the promoter.

4. Eukaryotic repressors directly block RNA polymerase from binding to the promoter.

5. The mechanisms of bacterial repressors and eukaryotic repressors and highly conserved and do not differ at all.

**I chose 4 and got it wrong

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Answer #1

Answer 3. Bacterial repressors directly block RNA polymerase from binding to the promoter.

Prokaryotic RNA polymerase action has been characterized by binding of the enzyme to the promoter to form a closed complex, melting of the DNA to form the open complex.

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