A number of weak interaction determine the stability of the DNA helix. These are hydrogen bonds between the bases and stacking interaction between adjacent base pairs.the hydrophobic interactions stacks bases on atop of another and these bases are attracted to the prior base.
In DNA molecule, the interaction of stacking bases with each other is via the Van der Waals forces. In a helical DNA huge number of bases interact and thus the strength of interaction is strong.
The base stacking is hydrophobic in nature. This interaction is more stronger in case of G C base pairs than that of A T base pairs.
Important thing is these are independent of the nature of base. Moreover these stacking interactions are favoured by the helical structure backbone, the five membered ring of ribose sugar. Thus it makes more energetically favoured.
Why does base stacking cause energetically favorable reactions in DNA?
When forming a DNA double helix, why is base stacking more important compared to H-bonding? Can you please help me understand this?
Question 1 1 pts Why is it important for DNA to have complementary base pairing? O Complementary base pairing allows base pairs to be packed in the most energetically favorable arrangement inside of the double helix structure. O Complementary base pairing will pair a purine with a purine, which are a similar width, thus they are able to hold the sugar-phosphate backbone an equal distance apart along the DNA molecule o Complementary base pairing is only important for maintaining the...
examine the model of DNA to the right. Two bases have been
extruded from base stacking. The white line outlines the sugar –
phosphate backbone along the chain. O is shown red, N blue, P
yellow and C gray.
a) based on the figure, describe the "handedness" of the helix
shown in region 1. What "type" of DNA is represented?
b) Based on the figure, describe the "handedness" of the helix
shown in region 2. What "type" of DNA is...
Understand why formation of α-helices and β-sheets is energetically favorable. Just need background info/summary.
All exothermic reactions are favorable. Using your own words, explain why some exothermic reactions are non-spontaneous even when they are all favorable. HTML Editor
Why might a DNA binding protein cause a protein to be toxic to the cell?
In which of the following reactions does water act as a Lewis Base? And reasons why? 1. HB+(aq)+H20(l)<---->B(aq)+H3O+(aq) 2.NH3(aq)+H2O(l)<--->NH4+(aq)+OH^-1(l) 3. Al^3+(aq)+6H20(l)<----->[Al(H2o)6]^3+(aq) 4.CO2(g)+H20(l)<------->H2CO3(aq)
why does dna polymerase only tun 3' to 5' direction?
ON) Why does DNA polymerase only run in the 3' to 5' direction? A - A - IX E 1 E 1 1 x X, - Paragraph 12pt -
QUESTION 17 Which of the following factors does not increase the Tm of DNA? Increase in stacking energy Increase in Absorbance Increase in % GC content Increase in salt concentration QUESTION 18 Which of the following statements is not true about glycolysis? Some reactions in Glycolysis use NADPH as a source of energy. The first step of glycolysis ensures that glucose is trapped inside the cell The Isomerization of DHAP to G3P makes the process of glycolysis efficient The end...
Does equating status with authority cause confusion? Why or why not?