Hello! Could you please draw the generic mechanism for Fischer esterification for the synthesis of benzocaine...
Hello!
Could you please draw the generic mechanism for Fischer
esterification for the synthesis of benzocaine from p-aminobenzoic
acid and ethanol catalysed by conc. H2SO4 and
if it is possible explain steps
Thank you so much!
Homework Answers
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Hello!
Could you please draw the generic mechanism for Fischer
esterification for the synthesis of benzocaine...
please help! thank you 47) Draw out the reaction mechanism for a Fischer esterification reaction with...
please help! thank you
47) Draw out the reaction mechanism for a Fischer esterification reaction with ethanol and benzoic acid in hot acidic conditions. Name the products. 48) Draw out the reaction mechanism for a Fischer esterification reaction when 5-hydroxyhexanoic acid is heated. Name the products if you feel ambitious.
Write the mechanism for the Fischer esterification of p-aminobenzoic acid with ethanol (good handwriting).
Write the mechanism for the Fischer esterification of p-aminobenzoic acid with ethanol (good handwriting).
Draw the structure of solid precipitate that forms when sulfuric acid is added to the solution...
Draw the structure of solid precipitate that forms
when sulfuric acid is added to the solution of p-aminobenzoic acid
in ethanol, "before the Esterification reaction" occurs.
CO H CO2CH CH3 conc. H2SO4 (catalyst) + CH3CH2OH + H20 (20.4) NH2 16 NH2 17 Ethyl p-aminobenzoate benzocaine) p-Aminobenzoic acid
Provide a stepwise mechanism for the multi-step synthesis of Benzocaine. The overall reaction can be seen...
Provide a stepwise mechanism for the multi-step synthesis of
Benzocaine. The overall reaction can be seen above. Please show
every step- thanks!
NH HN-C-CH; 1) KMnO4, MgSO4 HN-C-CH; (CH3CO)20 CH; 2) H2SO4 HO СН3 p-acetotoluidide COOH p-toluidine 1) HCI, 2) pH 7 H2O, A NH2 CH3CH,OH H2SO4 HOⓇO CH3CH2O o Benzocaine PABA We wish to oxidize the methyl group of p-toluidine but cannot do so without oxidizing the amino group (NH2). Consequently, the first step of our lab synthesis of...
Using the mechanism shown in Figure 1 as a template, draw out the mechanism for the...
Using the mechanism shown in Figure 1 as a template, draw out
the mechanism for the Fischer Esterification reaction that occurs
between butyric acid and isobutanol.
Figure 1. Mechanism for the Fischer Esterification of Acetic Acid and Ethanol :В -Н-в* он Н он -Н-В" дон ОН ОН он но ОН Note that every step is reversible! -:В COH2 от Figure 3. Generic Scheme for Fischer Esterification + R-OH R' R OH R cat. H2SO4 Neat 120°C, 1.5h
Hello everyone! I am sorry in advance for so many questions. There is experimental procedure for...
Hello everyone! I am sorry in advance for so many questions. There is experimental procedure for benzocaine synthesis from p-aminobenzoic acid: 12 ml of ethanol and 0.9 g of p-aminobenzoic acid was added and stirred until dissolving after 1 ml of conc. H2SO4 was added. Then it was heated under reflux for 40 minutes and cooled, next the mixture was transferred into 250 ml flask with 30 g of ice and 30 ml of water and 10 ml of 10%...
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How...
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How could you be exposed to this hazard? given the exposure, Level of risk what is negative (probability) 0–4 outcome? Suggested protective measure Isopentyl alcohol Glacial acetic acid conc. Sulfuric acid aq 5% sodium bicarbonate anhydrous sodium sulfate isopenyl acetate
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How...
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How could you be exposed to this hazard? given the exposure, Level of risk what is negative (probability) 0–4 outcome? Suggested protective measure Isopentyl alcohol Glacial acetic acid conc. Sulfuric acid aq 5% sodium bicarbonate anhydrous sodium sulfate isopenyl acetate
Fischer esterification lab question, Please help. Thank you in advance 1) In the synthesis of isopentyl...
Fischer esterification lab question, Please help. Thank you in
advance
1) In the synthesis of isopentyl ethanoate, whose reaction is
shown below
a) what is the purpose of the sodium bicarbonate solution in the
isolation step?
b) what is the purpose of adding molecular sieves to the
reaction?
c) what is the purpose adding sulfuric acid to the reaction?
d) why is acidic acid added in excess?
e) what is the purpose of conducting a semi-micro distillation
in the second...
Q7. Below is a reaction mechanism for the Fischer Esterification process. Identify the indicated steps (1...
Q7. Below is a reaction mechanism for the Fischer Esterification process. Identify the indicated steps (1 - 4), and what is general term for the intermediate A commonly known as? H -- CH CH CH پوت : كل ال OH2 :0: Step Name 1 2 3 A 2.5 marks Q8. Generally, esters have lower boiling points than their parent carboxylic acid do. Why might this be the case? 0.5 marks Q9. Name one reagent/method that can be used for removing...
please help! thank you
47) Draw out the reaction mechanism for a Fischer esterification reaction with ethanol and benzoic acid in hot acidic conditions. Name the products. 48) Draw out the reaction mechanism for a Fischer esterification reaction when 5-hydroxyhexanoic acid is heated. Name the products if you feel ambitious.
Draw the structure of solid precipitate that forms
when sulfuric acid is added to the solution of p-aminobenzoic acid
in ethanol, "before the Esterification reaction" occurs.
CO H CO2CH CH3 conc. H2SO4 (catalyst) + CH3CH2OH + H20 (20.4) NH2 16 NH2 17 Ethyl p-aminobenzoate benzocaine) p-Aminobenzoic acid
Provide a stepwise mechanism for the multi-step synthesis of
Benzocaine. The overall reaction can be seen above. Please show
every step- thanks!
NH HN-C-CH; 1) KMnO4, MgSO4 HN-C-CH; (CH3CO)20 CH; 2) H2SO4 HO СН3 p-acetotoluidide COOH p-toluidine 1) HCI, 2) pH 7 H2O, A NH2 CH3CH,OH H2SO4 HOⓇO CH3CH2O o Benzocaine PABA We wish to oxidize the methyl group of p-toluidine but cannot do so without oxidizing the amino group (NH2). Consequently, the first step of our lab synthesis of...
Using the mechanism shown in Figure 1 as a template, draw out
the mechanism for the Fischer Esterification reaction that occurs
between butyric acid and isobutanol.
Figure 1. Mechanism for the Fischer Esterification of Acetic Acid and Ethanol :В -Н-в* он Н он -Н-В" дон ОН ОН он но ОН Note that every step is reversible! -:В COH2 от Figure 3. Generic Scheme for Fischer Esterification + R-OH R' R OH R cat. H2SO4 Neat 120°C, 1.5h
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How could you be exposed to this hazard? given the exposure, Level of risk what is negative (probability) 0–4 outcome? Suggested protective measure Isopentyl alcohol Glacial acetic acid conc. Sulfuric acid aq 5% sodium bicarbonate anhydrous sodium sulfate isopenyl acetate
Risk assessment for: Synthesis of isoamyl acetate via Fischer esterification Student Name: Chemical Potential hazards How could you be exposed to this hazard? given the exposure, Level of risk what is negative (probability) 0–4 outcome? Suggested protective measure Isopentyl alcohol Glacial acetic acid conc. Sulfuric acid aq 5% sodium bicarbonate anhydrous sodium sulfate isopenyl acetate
Fischer esterification lab question, Please help. Thank you in
advance
1) In the synthesis of isopentyl ethanoate, whose reaction is
shown below
a) what is the purpose of the sodium bicarbonate solution in the
isolation step?
b) what is the purpose of adding molecular sieves to the
reaction?
c) what is the purpose adding sulfuric acid to the reaction?
d) why is acidic acid added in excess?
e) what is the purpose of conducting a semi-micro distillation
in the second...
Q7. Below is a reaction mechanism for the Fischer Esterification process. Identify the indicated steps (1 - 4), and what is general term for the intermediate A commonly known as? H -- CH CH CH پوت : كل ال OH2 :0: Step Name 1 2 3 A 2.5 marks Q8. Generally, esters have lower boiling points than their parent carboxylic acid do. Why might this be the case? 0.5 marks Q9. Name one reagent/method that can be used for removing...
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