Question

Feedback inhibition is defined as a mechanism of down-regulating enzyme activity by the accumulation of a...

Feedback inhibition is defined as a mechanism of down-regulating enzyme activity by the accumulation of a product earlier in the pathway. True or False, please explain

0 0
Add a comment Improve this question Transcribed image text
Answer #1

The answer is TRUE

Explanation: To ensure that the product concentration is regulated, in an enzyme catalysed reaction the product itself acts as the inhibitor of the enzyme activity thereby inhibiting its own production. The higher concentration of the product results in binding of the product to the allosteric site of the enzyme resulting in inhibition of the enzyme activity.

Eg. In human body cholesterol is produced in liver as it is an important structural component of the cells. But high amount of cholesterol in blood results in inhibition of cholesterol production in the liver.

Another example is production of ATP from glucose. If ATP is not being used up, ATP binds allosterically to the first enzyme of glucose breakdown resulting in inhibiting its activity.

Add a comment
Know the answer?
Add Answer to:
Feedback inhibition is defined as a mechanism of down-regulating enzyme activity by the accumulation of a...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions
ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT