X-linked hypophosphatemia (XLH) is due to a rare X-linked dominant form of rickets. A man with...
X-linked hypophosphatemia (XLH) is due to a rare X-linked dominant form of rickets. A man with XLH marries a healthy woman and they have a son with XLH. The MOST LIKELY explanation for this occurring is:
A. During spermatogenesis in the father, Meiosis I non-disjunction of the X chromosome generated a disomic sperm.
B. During spermatogenesis in the father, Meiosis II non-disjunction of the X chromosome resulted in a disomic sperm.
C. During oogenesis in the mother, Meiosis I non-disjunction of the X chromosome generated a nullosomic egg.
D. During spermatogenesis in the father, Meiosis II non-disjunction of the Y chromosome generated a disomic sperm.
E. During oogenesis in the mother, Meiosis I non-disjunction of the X chromosome created a disomic egg.
Homework Answers
The correct answer is-
C. During oogenesis in the mother, meiosis I non-disjunction of the X chromosome generated a nullosomic egg.
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X-linked hypophosphatemia (XLH) is due to a rare X-linked
dominant form of rickets. A man with...
Two normal parents have a son with hemophilia (an X-linked recessive disorder) that also has Klinefelter...
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An antigen found on red blood cells, Xg, is encoded by an X-linked allele (Xa) that...
An antigen found on red blood cells, Xg, is encoded by an
X-linked allele (Xa) that is dominant over an allele for the
absence of the antigen (X–). Scientists studied the inheritance of
these X-linked alleles in children with chromosome abnormalities to
determine where nondisjunction of the sex chromosomes occurred.
Match the genotypes of the parents and offspring to the parent
and cell division stage in which the nondisjunction must have
occurred. Shown as parent × parent = child.
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An antigen found on red blood cells, Xg, is encoded by an
X-linked allele (Xa) that is dominant over an allele for the
absence of the antigen (X–). Scientists studied the inheritance of
these X-linked alleles in children with chromosome abnormalities to
determine where nondisjunction of the sex chromosomes occurred.
Match the genotypes of the parents and offspring to the parent
and cell division stage in which the nondisjunction must have
occurred. Shown as parent × parent = child.
Nondisjunction...
In a routine prenatal screen, a clinical researcher finds that
the karyotype of cells derived from a fetus shows potential trisomy
(one of the chromosomes is present in 3 copies). It is not clear
whether the extra chromosome is chromosome 6 or 7 (because
chromosome 6 and 7 are quite similar in a simple chromosome spread
analysis). To determine whether the extra chromosome is chromosome
6 or 7, the researcher performs polymerase chain reaction followed
by RFLP analysis using DNA...
Vitamin D-resistant rickets is a genetic condition inherited as X-linked dominant. A husband has this Vitamin D-resistant rickets but his wife does not. What is the probability that their first child will be a: (4 pts) a) normal son? b) normal daughter? c) son with Vitamin D-resistant rickets? d) daughter with Vitamin D-resistant rickets DHU The eye is an example of an organ that develops from a complex series of developmental events, controlled and influenced by many genes. This process...
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