Question

You have isolated multiple cells from an individual and analyzed allelic expression of YFG. You find...

You have isolated multiple cells from an individual and analyzed allelic expression of YFG. You

find that some cells express the paternal allele, some cells express the maternal allele, and some

cells express both alleles. Which type of monoallelic expression is likely?

a. genomic imprinting

b. randome X-chromosome inactivation

c. random autosomal monoallelic expression

d. none of the above

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Answer #1

First lets understand the terms in the options.

Genomic imprinting: its a type of epigenetic process in which the expression of a gene occurs in a parent origic specific manner, a gene from paternal origin is expressed means, it is only always expressed.

random X -chromosome inactivation: X chromosome inactivation is transcriptional silencing of the expression of genes on one X chromosome which results in dosage compensation between XX and XY gene products. This happens in the embryonic developmental stage.

random autosomal monoallelic expression: It is random switching on and off of alleles. Here the single allelic expression occurs in somatic cells. So the expression is different in different cells.

Hence here the given situation is c) random autosomal monoallelic expression.

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