Question

11. In true wild-type (feral) yeast strains, mother cells switch cell type after cell division but daughter cells do not. The Ash1 protein was discovered to play a key role in this differential behavior. (7 points).
a) What is the function of the Ash1 protein and how did analyzing the phenotype of ash1 mutants enable us to deduce this?

Answer 1

The ash1 proteins which is found in the yeasts have many important roles like-

Ash1 is a transcription regulatory protein. It controls the transcription in the yeasts.

It is also required for pseudohyphaeal growth.

It has a role in mating type switching in which yhe yeast cell produces copy of the genome and become diploid.

The mutation causes alternation in these phenotypes which allow us to find it's necessity thereby knowing or deducing the functions.

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