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A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As...

A new potential heart medicine, code-named X-281, is being tested by a pharmaceutical company, Pharma-pill. As a research technician at Pharma-pill, you are told that X-281 is a monoprotic weak acid, but because of security concerns, the actual chemical formula must remain top secret. The company is interested in the drug's Ka value because only the dissociated form of the chemical is active in preventing cholesterol buildup in arteries.

What is pKb of the conjugate base of X-281? (Assume 25 ∘C)

Classify each of the following as a Lewis acid or a Lewis base.

  • Mn2+

  • CO

  • CO2

  • AlCl3

  • C N −

  • (CH3)3N

  • F −

  • (Lewis acids)

  • (Lewis bases)

You need to produce a buffer solution that has a pH of 5.25. You already have a solution that contains 10. mmol (millimoles) of acetic acid. How many millimoles of acetate (the conjugate base of acetic acid) will you need to add to this solution? The pKa of acetic acid is 4.74.

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