Question

Which of the following solvents would be good to use for 1H NMR analyses? (Check all that apply) acetone-d6 chloroform-d dimethyl sulfoxide deuterium oxide acetone

Answer 1

General guidance

Concepts and reason

• In nuclear magnetic resonance spectroscopy, the number of non \u2013 equivalent protons present in the structure can be identified with the help of proton NMR.

• The compound should be dissolved in solvent and recorded for NMR spectra.

• The solvent that used for dissolving compound should not interfere with the protons present in the compound.

• Therefore, the solvent should be selected in which it should not contain any hydrogen atom. So, deuterated solvents are used in ${}^{\\rm{1}}{\\rm{H}}$-NMR.

Fundamentals

The deuterated solvents do not contain any hydrogen atom. Therefore, the solvent cannot interfere with the protons present in it.

The solvents like, acetic acid \u2013 d₄, acetone \u2013 d₆, Acetonitrile \u2013 d₃, Benzene \u2013 d₆, chloroform \u2013 d, cyclohexane \u2013 d₁₇, deuterium oxide, N, N \u2013 dimethyl - formamide \u2013 d_l, dimethyl sulfoxide \u2013 d_G, methanol \u2013 d₄, methylene chloride \u2013 d₇ are used in NMR.

Step-by-step

Step 1 of 2

The solvents like acetone \u2013 d_6, chloroform \u2013 d and deuterium oxide are used for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis.

Explanation | Common mistakes | Hint for next step

The deuterated solvents were used for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis because it does not contain hydrogen atoms as hydrogen atoms are replaced by deuterium atoms. Therefore, it will not interfere with the spectra of compound. In that case, the above solvents are deuterated solvents that are used for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis.

Step 2 of 2

The solvents like dimethyl sulfoxide and acetone are not suitable for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis.

The solvents that would be good to use for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis are given below:

Acetone \u2013 d₆

Chloroform \u2013 d

Deuterium oxide

The solvents dimethyl sulfoxide and acetone are not deuterated. It will interfere with the spectra of compound. Therefore, those solvents cannot be used.

Answer

The solvents that would be good to use for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis are given below:

Acetone \u2013 d₆

Chloroform \u2013 d

Deuterium oxide

Answer only

The solvents that would be good to use for ${}^{\\rm{1}}{\\rm{H}}$-NMR analysis are given below:

Acetone \u2013 d₆

Chloroform \u2013 d

Deuterium oxide